Evidence map›Paper›PMID 41126637›Full record

ArticlePediatric pulmonology2025

Thoracotomies in Children in Low to Middle Income Countries: The Indications for Surgery.

Jacobus Botha, Pierre Goussard, Jacques Janson, Zane Ismail, Jin Kim, Francois Retief, Jonathan Burke, André Gie, Delano Rhode, Pawel Schubert and 1 more

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jacobus BothaFaculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.ORCID 0009-0006-9192-9764
Pierre GoussardDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.ORCID 0000-0003-1146-1307
Jacques JansonDepartment of Surgical Sciences, Division of Cardiothoracic Surgery, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Tygerberg, South Africa.ORCID 0000-0001-6029-9487
Zane IsmailDepartment of Surgical Sciences, Division of Cardiothoracic Surgery, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Tygerberg, South Africa.ORCID 0009-0001-1952-5662
Jin KimDepartment of Surgical Sciences, Division of Cardiothoracic Surgery, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Tygerberg, South Africa.
Francois RetiefDepartment of Anaesthesiology and Critical Care, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.ORCID 0000-0003-4179-9341
Jonathan BurkeDepartment of Anaesthesiology and Critical Care, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.
André GieDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.ORCID 0000-0002-9001-3387
Delano RhodeDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.ORCID 0009-0009-8841-3638
Pawel SchubertDivision of Anatomical Pathology, Department of Pathology, Tygerberg Hospital, National Health Laboratory Service, Faculty of Medicine and Health Science, Stellenbosch University, Cape Town, South Africa.ORCID 0000-0003-4422-7349
Savvas AndronikouDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-1015-9790

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

introductionThere is a scarcity of data on the utilization of thoracotomy for lung pathology in children in low- and middle-income countries (LMICs). These countries have high burdens of infectious diseases, especially tuberculosis, hydatic disease and Human immunodeficiency virus (HIV).

methodsThis is a retrospective descriptive study reviewing the indications for thoracotomy in a single center in a LMIC country. The study included all children under the age of 13 who underwent thoracotomy for pulmonary disease or vascular conditions affecting the airways at Tygerberg Hospital between January 2018 and December 2022. The indications for thoracotomy were classified into five groups: infectious, congenital, diagnostic, traumatic or neoplastic. Data collected included age, sex, HIV status, indication for the thoracotomy, procedures performed, complications of surgery and the final diagnosis after surgery.

resultsOne hundred seventy-two children who had undergone thoracotomy were studied with 182 thoracotomies performed. Infectious diseases (54.9%) were the most common indication for thoracotomy followed by congenital (35.2%), diagnostic (4.9%), traumatic (3.3%) and neoplastic (1.6%). The most common indication for thoracotomy was airway compression due to tuberculosis (TB) lymph nodes (21.4%), followed by hydatic cysts (20.9%) and vascular malformations (11.5%).

conclusionLMICs still face a significant burden of infectious and congenital diseases requiring thoracotomy, as compared to higher-income countries where neoplastic indications are most common. During the study period, hydatid cysts have become more prevalent and is now the most common indication for thoracotomy in the study setting. Thoracotomy can be safely performed in an LMIC setting with low morbidity and mortality, also in HIV-positive children.

Indexed as

Lung DiseasesThoracotomyAdolescentChildChild, PreschoolDeveloping CountriesFemaleHumansInfantMaleRetrospective Studiesbronchoscopyhydatic diseaselow‐middle‐income countriesthoracotomytuberculosis

Identifiers

PMID41126637
PMCPMC12547367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.