Evidence map›Paper›PMID 41126482›Full record

ArticleMagnetic resonance in medicine2026

Coronary Artery Blood Flow Imaging Using 3D Flow MRI.

Denise Lichthardt, Michaela Schmidt, Jens Wetzl, Peter Speier, Manuel Hein, Christopher Schuppert, Armin M Nagel, Daniel Giese

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Coronary Artery Blood Flow Imaging Using 3D Flow MRI.Magnetic resonance in medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Denise LichthardtInstitute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID https://orcid.org/0009-0003-4193-1805
Michaela SchmidtResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
Jens WetzlResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
Peter SpeierResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
Manuel HeinDepartment of Cardiology and Angiology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Christopher SchuppertDepartment of Diagnostic and Interventional Radiology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Armin M NagelInstitute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID https://orcid.org/0000-0003-0948-1421
Daniel GieseInstitute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

Funding

Siemens Healthineers
6 · The paper itself

Abstract

purposeIn this work, a 3D phase contrast (PC) technique is presented, which enables flow velocity measurements in three spatial directions, simultaneously covering the proximal left (LCA) and right (RCA) coronary arteries and yielding both morphological and flow information.

methodsData is acquired in a single diastolic cardiac phase during free breathing using an isotropic (Δx = 1.2 mm) 3D PC sequence with respiratory gating and compressed sensing acceleration (factor 14). The reference and flow-encoded datasets are obtained from separate scans instead of one interleaved measurement, enabling inter-scan motion correction through image co-registration. The proposed method is validated in a flow phantom and its feasibility is demonstrated in 16 volunteers (8 female, 59.3 ± 16.5 years) and 3 patients (1 female, 71.0 ± 9.6 years) with known CAD, where additional CTA and CT-FFR data were obtained. Data were acquired on a 3 T MRI system and post-processed using in-house developed software.

resultsFlow phantom experiments demonstrated good agreement between the proposed method and a typical 4D Flow acquisition. Mean average velocities in the proximal coronary arteries of volunteers were found to be 11.9 ± 3.3 cm s

conclusionThe feasibility of 3D-PC-MRI for non-invasive 3D blood flow velocity imaging in the coronary arteries is demonstrated. Simultaneous acquisitions of high-resolution morphology and velocities could offer new opportunities for diagnosing and monitoring CAD.

Indexed as

Coronary Artery DiseaseCoronary CirculationCoronary VesselsImaging, Three-DimensionalMagnetic Resonance ImagingAdultAgedAlgorithmsBlood Flow VelocityFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedPhantoms, Imagingcardiovascular magnetic resonance angiographycoronary artery diseasecoronary imagingflow imagingphase contrast MRI

Identifiers

PMID41126482
PMCPMC12746356

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.