ArticleJournal of cataract and refractive surgery2025
Corneal regeneration: How can we make further progress in corneal surgery with advanced therapies to avoid corneal substitution: ESCRS Binkhorst Medal Lecture 2023.
Article in Journal of cataract and refractive surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Corneal blindness affects millions globally and is one of the top 5 most common causes of blindness worldwide. Modern corneal transplantation techniques have made important progress in short-term and long-term outcomes, together with improvements in corneal banking, but there remains a high frequency of anatomical and functional failures. Corneal regeneration techniques offer significant advantages because they do not depend on donor tissue, may offer a better biological approach, and are free from complications related to allograft transplantation in humans. Our aim is to provide a perspective on the progress and improvements that have been made during recent years in corneal regeneration involving the ocular surface, corneal stroma, and corneal endothelium. Notably, the use of mesenchymal-derived stem cells from different origins, particularly from adipose tissue, has opened a new perspective in the treatment of corneal and ocular surface disorders.
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