Evidence map›Paper›PMID 41126409›Full record

ArticleJournal of cellular and molecular medicine2025

Identification of a Small Secretoneurin Derivative That Inhibits CaMKIIδ Activity.

Ilde Rugolo, Xin Shen, Thea Parsberg Støle, Anna Bergan-Dahl, Ornella Manfra, Marianne Lunde, Geir Christensen, Bjørn Dalhus, William E Louch, Anett H Ottesen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ilde RugoloAkershus Clinical Research Center (ACR), Division of Research and Innovation, Akershus University Hospital, Lørenskog, Norway.ORCID 0009-0007-6517-0173
Xin ShenInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Thea Parsberg StøleInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Anna Bergan-DahlInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Ornella ManfraInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Marianne LundeInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Geir ChristensenInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Bjørn DalhusDepartment of Microbiology, Oslo University Hospital, Oslo, Norway.
William E LouchInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Anett H OttesenAkershus Clinical Research Center (ACR), Division of Research and Innovation, Akershus University Hospital, Lørenskog, Norway.
Helge RøsjøAkershus Clinical Research Center (ACR), Division of Research and Innovation, Akershus University Hospital, Lørenskog, Norway.
Cathrine Rein CarlsonInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.

Funding

Akershus UniversitetssykehusNasjonalforeningen for FolkehelsenSouth-Eastern Norway Regional Health Authority 2015095Stiftelsen Kristian Gerhard Jebsen SKGJ-MED-024
6 · The paper itself

Abstract

Ventricular arrhythmias, a major cause of sudden cardiac death, are driven by Ca

Indexed as

Calcium-Calmodulin-Dependent Protein Kinase Type 2NeuropeptidesSecretogranin IIAnimalsBinding SitesCalciumCalmodulinHumansMyocytes, CardiacPhosphorylationProtein BindingRatsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CalmodulinNeuropeptidesSecretogranin IIsecretoneurinarrhythmiasCaMCaMKIIheart failurephospholambanRYRsecretoneurinSN

Identifiers

PMID41126409
PMCPMC12544700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.