Evidence map›Paper›PMID 41126369›Full record

ArticleAddiction science & clinical practice2025

Dissemination of an evidence-based motivational interviewing brief intervention for substance use disorders to HIV service organizations across the United States: protocol for a national-level cluster-randomized adaptive parallel-groups superiority experiment.

Hannah K Knudsen, Heather J Gotham, Elizabeth Solinger, Elizabeth Swan, Jen Brinker, Sheila V Patel, Stephen J Tueller, Michael Bradshaw, Jackie Mungo, Sarah Philbrick and 6 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Addiction science & clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hannah K KnudsenUniversity of Kentucky, 845 Angliana Avenue, Room 204, Lexington, KY, 40508, USA. hannah.knudsen@uky.edu.
Heather J GothamStanford University, 1070 Arastradero Rd, Palo Alto, CA, 94304, USA.
Elizabeth SolingerThe Ohio State University, 700 Ackerman, Columbus, OH, 43221, USA.
Elizabeth SwanThe Ohio State University, 700 Ackerman, Columbus, OH, 43221, USA.
Jen BrinkerThe Ohio State University, 700 Ackerman, Columbus, OH, 43221, USA.
Sheila V PatelRTI International, P. O. Box 12194, Research Triangle Park, NC, 27709-2194, USA.
Stephen J TuellerRTI International, P. O. Box 12194, Research Triangle Park, NC, 27709-2194, USA.
Michael BradshawRTI International, P. O. Box 12194, Research Triangle Park, NC, 27709-2194, USA.
Jackie MungoRTI International, P. O. Box 12194, Research Triangle Park, NC, 27709-2194, USA.
Sarah PhilbrickRTI International, P. O. Box 12194, Research Triangle Park, NC, 27709-2194, USA.
Tom DonohoeUniversity of California, Los Angeles, 10911 Weyburn Avenue, Suite 200, Los Angeles, CA, 90024, USA.
Thomas E FreeseUniversity of California, Los Angeles, 10911 Weyburn Avenue, Suite 200, Los Angeles, CA, 90024, USA.
Beth A RutkowskiUniversity of California, Los Angeles, 10911 Weyburn Avenue, Suite 200, Los Angeles, CA, 90024, USA.
Mathew R RoosaRoosa Consulting, Beacon, NY, USA.
Kathryn J SpeckUniversity of Nebraska Public Policy Center, 215 Centennial Mall South, Suite 401, Lincoln, NE, 68588, USA.
Bryan R GarnerThe Ohio State University, 700 Ackerman, Columbus, OH, 43221, USA.

Funding

Identifying and Disseminating Substance, Treatment, and Strategy (STS) Recommendations to AIDS Service OrganizationsR01DA044051 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI GARNER, BRYAN R · 2018 to 2022
$3.8M
NIDA NIH HHS R01 DA044051NIDA NIH HHS R01DA044051
6 · The paper itself

Abstract

backgroundGiven the high prevalence of substance use disorders (SUDs) among people with HIV, integration of evidence-based SUD services within HIV service settings is needed. Federally-funded training and technical assistance centers, such as the Health Resources and Services Administration-funded AIDS Education and Training Center (AETC) network, are part of the support system that deliver strategies to promote the uptake of evidence-based interventions. Previously, our program of research supported (1) the effectiveness of facilitation for improving both the implementation and effectiveness of a motivational interviewing-based brief intervention for SUDs in HIV service organizations (HSOs), (2) motivational interviewing as having the best setting-intervention fit for HSOs, and (3) distributing educational materials as having the best setting-strategy fit for AETCs. Because exploration and adoption/preparation are phases that must occur before implementation and sustainment, we seek to test the effectiveness of facilitation to augment an initial distributing educational materials dissemination strategy.

methodsUsing a multi-cohort cluster-randomized adaptive parallel-groups superiority experiment design, our aim is to test the effectiveness of augmenting a standard distributing educational materials dissemination strategy with a brief exploration facilitation dissemination strategy to support implementation of a motivational interviewing-based brief intervention. For each rollout, HSOs not responding to the distributing educational materials strategy will be randomized to either (a) receive no further intervention or (b) receive the exploration facilitation strategy. Assessed 4-months post-dissemination, the primary dissemination outcome is organizational-level adoption/preparation of the intervention (i.e., 1 + HSO staff downloads the manual and/or enrolls in the online asynchronous training). The secondary dissemination outcome is organization-level exploration of the intervention (i.e., 1 + HSO staff opens the dissemination email). DISCUSSION: Before evidence-based interventions are implemented in practice to improve health outcomes, they must first be successfully disseminated and then explored and adopted by service organizations and providers. Because training and technical assistance centers have limited resources for dissemination efforts, effective adaptive dissemination strategies that utilize limited resources are needed. If we find the exploration facilitation strategy to be an effective adjunct to the distributing educational materials strategy, we hope that this adaptive dissemination strategy can be widely adopted and implemented by training and technical assistance centers.

trial registrationOpen Science Framework: https://osf.io/urgzd . Registered 1/30/2025. PROTOCOL VERSION: 1/30/2025 Version 1.

Indexed as

HIV InfectionsMotivational InterviewingSubstance-Related DisordersAdherence InterventionsEquivalence Trials as TopicEvidence-Based PracticeHumansRandomized Controlled Trials as TopicUnited StatesAdoptionBrief interventionDisseminationExplorationFacilitationHIVMotivational interviewingSubstance use disorders

Identifiers

PMID41126369
PMCPMC12548271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.