Evidence map›Paper›PMID 41126253›Full record

ArticleJournal of medical case reports2025

Post-coronavirus disease bilateral endogenous fungal endophthalmitis with full visual acuity recovery: a case report.

Jessica L Leyva, Rodrigo T Celis, Adriana Vargas, Rodrigo J Celis, Gloria Guida, David A Forero-Peña

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In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jessica L Leyva *"Luis Razetti" School of medicine, Central University of Venezuela, Caracas, Venezuela. jessileyva@gmail.com.ORCID http://orcid.org/0000-0002-3823-8466
Rodrigo T Celis"Luis Razetti" School of medicine, Central University of Venezuela, Caracas, Venezuela.
Adriana VargasOphthalmologic Institute of Retina and Vitreous, Valencia, Venezuela.
Rodrigo J Celis *Ophthalmologic Institute of Retina and Vitreous, Valencia, Venezuela.
Gloria GuidaUniversity of Carabobo, Carabobo, Venezuela.
David A Forero-PeñaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreasing reports and case series describe cases of endogenous endophthalmitis (EE) following severe acute respiratory syndrome coronavirus 2 infection. Endogenous endophthalmitis is a severe ophthalmologic pathology caused by bacteremic or fungemic seeding of the eye, often in immunocompromised patients. Delayed treatment can lead to permanent visual impairment. We report the diagnosis and management of a case of fungal endogenous endophthalmitis with voriconazole and surgery that led to complete visual acuity recovery. CASE PRESENTATION: We present a case of post-coronavirus disease 2019 bilateral fungal endogenous endophthalmitis due to Candida albicans in a 64-year-old Caucasian male patient. Upon arrival, he had a visual acuity of 6/200 and slow pupillary light reflex. Ocular examination revealed conjunctival hyperemia, keratic precipitates, moderate vitritis with cotton wool spots, intraretinal hemorrhages, and foci of chorioretinitis.

conclusionTreatment for endogenous endophthalmitis is often delayed because cultures frequently yield negative results. Early diagnosis is key for better outcomes in endogenous endophthalmitis. This case highlights the need for a high index of suspicion for endogenous endophthalmitis in patients with coronavirus disease 2019 to ensure early diagnosis and timely intervention.

Indexed as

CandidiasisCOVID-19EndophthalmitisEye Infections, FungalVoriconazoleAntifungal AgentsCandida albicansHumansMaleMiddle AgedSARS-CoV-2Treatment OutcomeVisual AcuityVitrectomyAntifungal AgentsVoriconazoleCase reportEndogenous endophthalmitisPost-COVIDVisual acuity

Identifiers

PMID41126253
PMCPMC12542003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.