Evidence map›Paper›PMID 41126252›Full record

ArticleBMC biology2025

Hemipteran insects experience recurrent and synergistic molecular evolution adapting to diet shift.

Ling Ma, Yuange Duan, Fanding Gao, Xinyu Li, Tianyou Zhao, Shangyuan Wu, Li Tian, Fan Song, Wanzhi Cai, Hu Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ling Ma *Department of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Yuange Duan *Department of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Fanding GaoDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Xinyu LiDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Tianyou ZhaoDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Shangyuan WuDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Li TianDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Fan SongDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Wanzhi CaiDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China. caiwz@cau.edu.cn.
Hu LiDepartment of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China. tigerleecau@hotmail.com.ORCID http://orcid.org/0000-0001-8590-1753

Funding

Expert Workstation in Zhaotong, Yunnan No. 2021ZTYX05National Natural Science Foundation of China No. 31922012Sanya Yazhou Bay Science and Technology City No. SYND-2022-04the Pests and Diseases Green Prevention and Control Major Special Project No. 110202201018[LS-02]the Postdoctoral Fellowship Program of CPSF No. GZC20241945
6 · The paper itself

Abstract

backgroundHemiptera is an insect order with extremely high physiological and behavioral diversity. Feeding traits have switched and reversed multiple times, but the molecular basis governing this phenotypical change remains unclear.

resultsWe obtained the high-quality genomes and salivary gland transcriptomes of two essential biocontrol agents, Eocanthecona furcellata and Arma custos (Hemiptera: Heteroptera: Pentatomidae: Asopinae). This subfamily represents a typical insect clade with the reversal of feeding traits from phytophagy to zoophagy. Combined with public data of an additional 38 phylogenetically related insects and salivary gland transcriptomes of representative species, we performed a comprehensive analysis on the molecular evolution of feeding traits. We defined a set of diet-related gene groups and found that these genes were repetitively expanded in zoophagous species and experienced fast evolution and positive selection during diet reversal in the E. furcellata-A. custos clade. Transcriptomic analysis revealed dynamic upregulation of diet-related gene expression in zoophagous species, and further endeavor narrowed down the candidates to several genes, like trypsin and carboxypeptidase, which might be involved in diet reversal.

conclusionsIn conclusion, the evolution of zoophagy in Hemiptera and the reversal of feeding traits might require the synergistic regulations at both genomic and transcriptomic levels. Our study provides a potential connection between genotype and phenotype and advances the understanding of the adaptive evolution of zoophagous insects.

Indexed as

DietEvolution, MolecularHemipteraHeteropteraAnimalsFeeding BehaviorPhylogenyTranscriptomeGenome evolutionHemipteraReversalSalivary gland transcriptomeSynergisticZoophagous

Identifiers

PMID41126252
PMCPMC12542004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.