ArticleBMC women's health2025
Clinical manifestations and quality of life of postmenopausal women with severe osteoporosis: a cross-sectional study on the Vietnamese population.
Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
backgroundOsteoporosis, a systemic skeletal disorder characterized by reduced bone mineral density (BMD) and micro-architectural deterioration, significantly increases fracture risk. Postmenopausal women are particularly susceptible due to estrogen deficiency, which accelerates bone resorption. This study evaluates the clinical manifestations and quality of life (QoL) of Vietnamese women with severe postmenopausal osteoporosis using the Quality of Life Questionnaire of the European Foundation for Osteoporosis (Qualeffo-41).
methodsA cross-sectional study was conducted from February to May 2023 at Nghe An Friendship General Hospital, Vietnam. Seventy-one postmenopausal women aged 48-94 years with severe osteoporosis (BMD T-score ≤ -2.5 SD and history of fracture) were included. Exclusion criteria encompassed secondary osteoporosis, invasive procedures, and the inability to complete the questionnaire. Clinical data and QoL were assessed using the Vietnamese version of the Qualeffo-41 questionnaire.
resultsParticipants had an average age of 70 years and an average BMI of 19.99 ± 2.80 kg/m
conclusionThis study underscores the substantial impact of severe osteoporosis on QoL in Vietnamese postmenopausal women, emphasizing the critical role of fracture prevention and BMD management. Future research should explore targeted interventions to mitigate these burdens and enhance patient outcomes.
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