Evidence map›Paper›PMID 41126203›Full record

ArticleBMC women's health2025

The relationship between cold sensitivity and menstrual cycle in Japanese women under normothermic conditions.

Fumio Yamazaki, Mei Tokunaga, Hibiki Nakahara, Yuzusa Fujii

Abstract read
In one paragraph

Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fumio YamazakiExercise Physiology Laboratory, Faculty of Nursing and Human Nutrition, Yamaguchi Prefectural University, 6-2-1 Sakurabatake, Yamaguchi, 753-8502, Japan. fsone@yp4.yamaguchi-pu.ac.jp.
Mei TokunagaExercise Physiology Laboratory, Faculty of Nursing and Human Nutrition, Yamaguchi Prefectural University, 6-2-1 Sakurabatake, Yamaguchi, 753-8502, Japan.
Hibiki NakaharaExercise Physiology Laboratory, Faculty of Nursing and Human Nutrition, Yamaguchi Prefectural University, 6-2-1 Sakurabatake, Yamaguchi, 753-8502, Japan.
Yuzusa FujiiExercise Physiology Laboratory, Faculty of Nursing and Human Nutrition, Yamaguchi Prefectural University, 6-2-1 Sakurabatake, Yamaguchi, 753-8502, Japan.

Funding

Japan Society for the Promotion of Science 25K14772
6 · The paper itself

Abstract

backgroundMany Japanese women report experiencing sensations of cold in their daily lives. We conducted a two-part study to determine whether the common complaint of coldness changes with menstrual cycle in women.

methodsIn the first part of the study (Part 1), we conducted an Internet survey that included 627 women aged 15 to 69 years. Participants answered a questionnaire about the relationship between coldness and menstrual cycle. The questions regarding coldness were used to classify participants into a cold-sensitive group (C group, n = 273) and a normal group (N group, n = 354). In the second part (Part 2), we surveyed 20 young adult women (C, n = 10; N, n = 10) on the cold sensation of 11 body parts. Furthermore, we tested cold sensitivity in the luteal and follicular phases at room temperature (25 ± 1 °C). Cold sensitivity was evaluated by calculating the slope of the relationship between thermal sensation and hand skin temperature during hand cooling in water (from 31 °C to 23 °C).

resultsIn Part 1, no association was found between the number of applicable coldness-related questions and age. The highest percentage of respondents in both groups answered that “coldness is not related to menstruation” (C, 64.8%; N, 48.0%). In Part 2, no difference was found in the cold sensations at 11 body sites between the luteal and follicular phases in the C and N groups; however, a decrease in sublingual temperature (-0.28 ± 0.22 °C) was noted at the onset of the follicular phase. The cold sensations at 31 °C in the precooling period were significantly stronger in the C group than the N group under both menstrual cycle conditions, whereas cold sensitivity in the hand was similar between the luteal and follicular phases in both groups.

conclusionsThese findings suggest that changes in body temperature with menstrual cycle do not affect overall cold sensation or hand cold sensitivity, regardless of the presence or absence of cold constitution, under normothermic conditions.

Indexed as

Cold TemperatureMenstrual CycleThermosensingAdolescentAdultAgedEast Asian PeopleFemaleHumansJapanLuteal PhaseMiddle AgedSkin TemperatureSurveys and QuestionnairesYoung AdultAge differenceCold constitutionCore temperatureMenstrual cycleSkin temperatureThermal sensation

Identifiers

PMID41126203
PMCPMC12541946

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.