Evidence map›Paper›PMID 41126126›Full record

SynthesisBMC infectious diseases2025

Global mapping of sexually transmitted Chlamydia trachomatis disease: a systematic review and meta-analysis.

Fatemeh Sameni, Tala Hajiarab, Sara Bayat, Mehrshad Ahmadi, Alex van Belkum, Ali Dadashi, Mehdi Goudarzi, Masoud Dadashi

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Worldwide prevalence ofNew microbes and new infections · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Fatemeh SameniInfectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tala HajiarabDepartment of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Sara BayatDepartment of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Mehrshad AhmadiDepartment of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Alex van BelkumIndependent Microbiology Consultant, Jan van Goyenplein 31, 2231 MM, Rijnsburg, The Netherlands.
Ali DadashiSchool of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehdi GoudarziDepartment of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Masoud DadashiDepartment of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran. m_d6512@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChlamydia trachomatis (C. trachomatis) is known as a leading cause of one of the most prominent sexually transmitted diseases (STD) worldwide. A meta-analysis was performed in this study to comprehensively determine the prevalence of C. trachomatis in the STD population.

methodPubMed/Medline, Embase, and Web of Science databases were used to conduct an extensive literature search on relevant papers published from 2000 to 2023. After that, statistical analysis was performed utilizing comprehensive meta-analysis (CMA) software (version 2.0, Biostat, USA) to report the global prevalence of C. trachomatis in the STD population.

resultIn prevalence studies involving an overall number of 40,159 STD individuals, 17,289 C. trachomatis isolates were collected in 86 countries worldwide, either by culture or by indirect DNA testing. The pooled prevalence of C. trachomatis within the global STD population was 41.6% (95% CI,40.1–43%), while a higher rate was recorded for males (12807 vs. 18871). The prevalence of C. trachomatis infection was highest in Oceania, followed by Europe, America, Asia, and Africa (49.9%, 46.3%, 41.3%, 41.1%, and 36.1%, respectively). According to data from case reports and case series, lymphogranuloma venereum (LGV) and human immunodeficiency virus (HIV) infection were the most common concurrent diseases and co-infections.

conclusionThe elevated prevalence of C. trachomatis in 86 countries suggests that innovative screening and infection-prevention programs are required to reduce the burden of this clinically very significant bacterial infection. Our results support the demand for further fundamental investigations in this area especially among HIV-positive patients.

Indexed as

Chlamydia InfectionsChlamydia trachomatisSexually Transmitted DiseasesFemaleGlobal HealthHumansMalePrevalenceChlamydia trachomatisMeta-analysisSexually transmitted diseasesSTD

Identifiers

PMID41126126
PMCPMC12542354

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.