Evidence map›Paper›PMID 41126114›Full record

ArticleBMC ophthalmology2025

Differentiation of optic disc edema and pseudopapilledema with deep learning on near-infrared reflectance images.

Cumhur Ozbas, Furkan Kirik, Ersin Akbulut, Gulsah Eldemir, Betul Tugcu, Mehmet H Ozdemir

Abstract read
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Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Cumhur OzbasDepartment of Ophthalmology, Sanliurfa Training and Research Hospital, Yenice, Yenice Road No:1, Sanlıurfa, Eyyubiye, 63250, Turkey. cumhurozbas92@gmail.com.ORCID http://orcid.org/0000-0002-5599-0422
Furkan KirikDepartment of Ophthalmology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-5846-8536
Ersin AkbulutDepartment of Ophthalmology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-9214-5458
Gulsah Eldemir, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-2897-2130
Betul TugcuDepartment of Ophthalmology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-2858-6130
Mehmet H OzdemirDepartment of Ophthalmology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-1719-4265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to develop an artificial intelligence-based deep learning (DL) algorithm using near-infrared reflectance (NIR) images to differentiate between optic disc edema and pseudopapilledema, and to evaluate the diagnostic performance of the developed model.

methodsNIR images were divided into 2 groups for training and testing of the model. 85% (714 images) were used for training the model and 15% (126 images) for testing the trained model. Sensitivity, specificity and accuracy of the model were calculated in detecting optic disc edema, pseudopapilledema and normal optic discs. Receiver operating characteristic curve and area under the curve (AUC) values were also analyzed.

resultsThe developed model was tested with 24 optic disc edema, 52 pseudopapilledema, and 50 normal optic disc images not used in training. Sensitivities were 100%, 98%, and 96%; specificities were 99%, 97%, and 100%; and accuracy rates were 99%, 98%, and 98%, respectively. In addition, the AUC values of the groups were 0.995 (95% Confidence interval [CI]: 0.98-1); 0.983 (95% CI: 0.96-1); and 0.973 (95% CI: 0.94-1).

conclusionsThe developed DL model demonstrated high diagnostic performance in distinguishing optic disc edema and pseudopapilledema using NIR images and may serve as a reliable clinical decision support tool.

Indexed as

Deep LearningEye Diseases, HereditaryOptic DiskOptic Nerve DiseasesPapilledemaAdultAlgorithmsDiagnosis, DifferentialFemaleHumansMaleMiddle AgedROC CurveSensitivity and SpecificitySpectroscopy, Near-InfraredYoung AdultArtificial intelligenceDeep learningNear infrared reflectanceOptic disc edemaPseudopapilledema

Identifiers

PMID41126114
PMCPMC12542413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.