ArticleBMC geriatrics2025
Prognostic predictors of mortality among individuals with advanced dementia residing in nursing homes: a prospective cohort study.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundLimited research has explored survival outcome predictions in those with advanced dementia within the Chinese population. A longitudinal cohort study was performed to better characterize the end-of-life trajectories of Chinese individuals with advanced dementia, providing a means of identifying prognostic predictors of 32-month mortality among nursing home residents in Chengdu, China.
methodsThis study enrolled 186 residents who met the inclusion criteria, with all having advanced dementia. Participants were evaluated at baseline and followed until death or the study’s conclusion. Demographic information, health and medical status, and mortality-related data were assessed. Kaplan-Meier survival analyses and Cox proportional hazards models were applied to approximate survival rates and identify predictive factors.
resultsThe median age of enrolled participants was 83.5 years, with females comprising 60.2% of the cohort. The overall survival rate was 52.0%. After adjusting for all variables, three significant prognostic factors were identified: oral nutritional supplement use (HR: 3.006, 95% CI: 1.593–5.671, p = 0.001), albumin concentration (HR: 0.914, 95% CI: 0.861–0.970, p = 0.003), and memantine use (HR: 0.416, 95% CI: 0.190–0.907, p = 0.028). Survival at 6 months, 1 year, and 2 years was significantly higher in the memantine group versus non-users.
conclusionsThe present study identified key prognostic factors for mortality in Chinese nursing home residents with advanced dementia. Notably, memantine use emerged as a protective factor, marking the first demonstration of its potential survival benefit in this population. These findings may aid healthcare professionals in optimizing resource allocation and care strategies for individuals at the end of life.
trial registrationChiCTR2100041764 (Chinese Clinical Trial Registry). Registered 4 January 2021.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.