Evidence map›Paper›PMID 41126003›Full record

ReviewNeuropsychology review2025

Digital Tools for Mild Cognitive Impairment: A Systematic Review and Meta-analysis of Diagnostic Accuracy and Methodological Challenges.

Aurora Bonvino, Ester Cornacchia, Giorgia Francesca Scaramuzzi, Daphne Gasparre, Valerio Manippa, Davide Rivolta, Paolo Taurisano

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuropsychology review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Editorial: Mild cognitive impairment and cognitive aging.Frontiers in behavioral neuroscience · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aurora Bonvino *Dipartimento di Biomedicina Traslazionale e Neuroscienze - DiBraiN, Università Degli Studi Di Bari, Bari, Italy.ORCID http://orcid.org/0000-0001-8772-5992
Ester Cornacchia *Dipartimento di Biomedicina Traslazionale e Neuroscienze - DiBraiN, Università Degli Studi Di Bari, Bari, Italy.ORCID http://orcid.org/0009-0002-0421-3348
Giorgia Francesca ScaramuzziDipartimento di Biomedicina Traslazionale e Neuroscienze - DiBraiN, Università Degli Studi Di Bari, Bari, Italy. g.scaramuzzi6@phd.uniba.it.ORCID http://orcid.org/0009-0004-9518-9252
Daphne GasparreDipartimento di Biomedicina Traslazionale e Neuroscienze - DiBraiN, Università Degli Studi Di Bari, Bari, Italy.ORCID http://orcid.org/0009-0001-0443-2527
Valerio ManippaDipartimento di Medicina di Precisione e Rigenerativa e Area Jonica - DiMePRe-J, Università Degli Studi Di Bari, Bari, Italy.ORCID http://orcid.org/0000-0003-3892-5212
Davide RivoltaDipartimento di Scienze Della Formazione, Psicologia e Comunicazione - For.Psi.Com, Università Degli Studi Di Bari, Bari, Italy.ORCID http://orcid.org/0000-0002-9969-9135
Paolo TaurisanoDipartimento di Biomedicina Traslazionale e Neuroscienze - DiBraiN, Università Degli Studi Di Bari, Bari, Italy.ORCID http://orcid.org/0000-0001-6140-9326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild cognitive impairment (MCI) represents an intermediate stage between typical aging and early cognitive decline. As such, an early and accurate diagnosis is essential in making timely interventions. Digital tools, including mobile applications, web platforms, wearable devices, and artificial intelligence-driven systems, have been developed and validated to capture multidimensional data, offering innovative screening solutions. This meta-analysis aims to evaluate the diagnostic accuracy of digital tools for MCI detection in different populations and settings, with a particular focus on three key issues: (i) the overall diagnostic performance of digital tools, (ii) the influence of methodological quality of studies, and (iii) the impact of demographic factors and familiarity with technologies on diagnostic accuracy. This meta-analysis assessed diagnostic accuracy across 32 studies, reporting pooled sensitivity (0.808, 95% CI: 0.775-0.838) and specificity (0.795, 95% CI: 0.757-0.828), but with considerable heterogeneity (I

Indexed as

Cognitive declineDigital assessmentEarly diagnosisMCINeurocognitive disordersReliability

Identifiers

PMID41126003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.