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ArticleSocial psychiatry and psychiatric epidemiology2026

Prevalence of sexual minorities and its association with mental health among Chinese adolescents: a nationally representative cross-sectional study.

Wenjian Lai, Li Li, Jingman Shi, Herui Wu, Yuwei Zhang, Guoliang Huang, Wanxin Wang, Lan Guo, Wei-Hong Zhang, Ciyong Lu

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Article in Social psychiatry and psychiatric epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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10 authors.

Wenjian Lai *Department of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China.
Li Li *Maternity and Children Health Care Hospital of Luohu District, No.2013 Taibai Rd, Shenzhen, 518019, China.
Jingman ShiDepartment of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China.
Herui WuDepartment of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China.
Yuwei ZhangDepartment of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China.
Guoliang HuangCenter for Adverse Drug Reaction Monitoring of Guangdong, Guangzhou, China.
Wanxin WangDepartment of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China.
Lan GuoDepartment of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China.
Wei-Hong ZhangFaculty of Medicine and Health Sciences, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.
Ciyong LuDepartment of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China. luciyong@mail.sysu.edu.cn.

Funding

National Natural Science Foundation of China 81761128030
6 · The paper itself

Abstract

purposeMental health disparities in sexual minority adolescents have emerged as public health concerns worldwide. This study aimed to investigate the prevalence of sexual minorities and its association with mental health problems among Chinese adolescents, and explored sex difference and the role of social support in the foregoing associations.

methodsA total of 66,812 adolescents were included from eight provinces via a multi-stage, stratified cluster, random sampling method in 2021. Sampling weights were used to estimate the prevalence, and propensity score-weighted multivariable logistic regression models were conducted in the analyses. Stratified analyses by sex and social support were also conducted.

resultsOf the total sample, the mean (SD) age was 14.9 (1.8) years, with 33,206 boys (52.4%) and 33,721 girls (47.6%). The weighted prevalence of adolescents who identified as heterosexual, homosexual, bisexual and unsure was 80.4%, 2.0%, 9.1% and 8.5%, respectively. Compared with heterosexual, homosexual adolescents were associated with higher odds of depressive symptoms (propensity score-weighted [PSW] adjusted odds ratio [AOR], 2.64; 95% CI, 2.17-3.22), anxiety symptoms (PSW AOR, 1.88; 95% CI, 1.55-2.29), non-suicidal self-injury (PSW AOR, 1.83, 95% CI, 1.55-2.17), suicidal ideation (PSW AOR, 2.34; 95% CI, 1.98-2.77), and suicidal attempt (PSW AOR, 2.39, 95% CI, 1.93-2.98). Sex-stratified analyses showed stronger associations between sexual minority status and most mental health problems for boys than for girls. Sexual minority adolescents with low social support were associated with poorer mental health compared to those with high social support.

conclusionHomosexual and bisexual adolescents experienced poorer mental health status than their heterosexual peers, with homosexual adolescents showing slightly stronger associations with mental health risks than bisexual adolescents. More support from family, school and society are recommended to improve the well-being of sexual minority adolescents.

Indexed as

Mental DisordersMental HealthSexual and Gender MinoritiesAdolescentChinaCross-Sectional StudiesDepressionEast Asian PeopleFemaleHumansMalePrevalenceSocial SupportSuicidal IdeationAdolescentsMental healthSexual minoritySocial support

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