Evidence map›Paper›PMID 41125445›Full record

ArticleGenome research2026

Epigenetic and evolutionary features of ape subterminal heterochromatin.

DongAhn Yoo, Katherine M Munson, Evan E Eichler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Germline hypomethylation shapes dynamic CpG reservoirs in ape genomes.bioRxiv : the preprint server for biology · 2026
    Article
  4. A Complete Genome for the Common Marmoset.bioRxiv : the preprint server for biology · 2026
    Article
  5. Origin and evolution of acrocentric chromosomes in human and great apes.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

DongAhn YooDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA.ORCID 0000-0003-0033-3721
Katherine M MunsonDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA.ORCID 0000-0001-8413-6498
Evan E EichlerDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA; ee3@uw.edu.ORCID 0000-0002-8246-4014

Funding

Sequence and Assembly of Segmental DuplicationsR01HG002385 · NHGRI · UNIVERSITY OF WASHINGTON · PI Evan Eichler · 2001 to 2026
$13.3M
Sequence-resolved structural variation of human genomesR01HG010169 · NHGRI · UNIVERSITY OF WASHINGTON · PI Evan Eichler · 2018 to 2026
$4.5M
NHGRI NIH HHS R01 HG002385NHGRI NIH HHS R01 HG010169
6 · The paper itself

Abstract

Many African great ape chromosomes possess large subterminal heterochromatic caps at their telomeres that are conspicuously absent from the human lineage. Leveraging the complete sequences of great ape genomes, we characterize the organization of subterminal caps and reconstruct the evolutionary history of these regions in chimpanzees and gorillas. Detailed analyses of the composition of the associated terminal 32 bp satellite array from chimpanzee (termed pCht) and intervening segmental duplication (SD) spacers confirm two independent origins in the

Indexed as

Epigenesis, GeneticEvolution, MolecularHeterochromatinHominidaeTelomereAnimalsDNA MethylationDNA, SatelliteGorilla gorillaHumansPan paniscusPan troglodytesPhylogenyDNA, SatelliteHeterochromatin

Identifiers

PMID41125445
PMCPMC12758386

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.