Evidence map›Paper›PMID 41125371›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Mycophenolate Mofetil-induced Multiple Ileal Ulcerations in a Renal Transplant Recipient: Diagnostic Challenges and Management.

Misato Shimizu, Masafumi Kitamura, Yusuke Ono, Takuma Kobayashi, Takashi Ueno, Yuka Kagaya, Masahiro Okada, Hirotsugu Sakamoto, Tomonori Yano

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Misato ShimizuDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Masafumi KitamuraDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Yusuke OnoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Takuma KobayashiDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Takashi UenoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Yuka KagayaDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Masahiro OkadaDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Hirotsugu SakamotoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Tomonori YanoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a kidney transplant recipient with recurrent bleeding due to multiple ileal ulcerations associated with mycophenolate mofetil (MMF). Symptoms persisted despite surgical resection and embolization. Double-balloon enteroscopy revealed multiple ulcerations, and a biopsy helped exclude other causes. The discontinuation of MMF led to rapid symptom resolution and healing of the ulceration. Intestinal complications after renal transplantation vary, and MMF-induced enteritis, although rare, should be considered. This case highlights the diagnostic value of enteroscopy in identifying drug-induced small intestinal injuries and underscores the importance of including MMF in the differential diagnosis of post-transplant gastrointestinal bleeding.

Indexed as

Ileal DiseasesImmunosuppressive AgentsKidney TransplantationMycophenolic AcidUlcerDouble-Balloon EnteroscopyGastrointestinal HemorrhageHumansIleumImmunosuppressive AgentsMycophenolic Aciddouble-balloon enteroscopydrug-induced enteritisgastrointestinal bleedingmycophenolate mofetilorgan transplantationsmall intestinal ulceration

Identifiers

PMID41125371
PMCPMC13294607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.