Evidence map›Paper›PMID 41125370›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Ulcerative Colitis after Administration of Dupilumab, an Anti-interleukin-4 Receptor Subunit α Monoclonal Antibody.

Hikaru Mamizu, Maiko Mamizu, Daisuke Ishikawa, Hidenori Kawakami, Toshiki Furukawa, Takashi Ishida, Takeshi Sakai

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hikaru MamizuDepartment of Internal Medicine, Niigata Prefectural Central Hospital, Japan.
Maiko MamizuDepartment of Internal Medicine, Niigata Prefectural Central Hospital, Japan.
Daisuke IshikawaDepartment of Internal Medicine, Niigata Prefectural Central Hospital, Japan.
Hidenori KawakamiDepartment of Internal Medicine, Niigata Prefectural Central Hospital, Japan.
Toshiki FurukawaDepartment of Internal Medicine, Niigata Prefectural Central Hospital, Japan.
Takashi IshidaDepartment of Internal Medicine, Niigata Prefectural Central Hospital, Japan.
Takeshi SakaiDepartment of Diagnostic Pathology, Niigata Prefectural Central Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 38-year-old woman who visited our hospital because of persistent bloody stool one month after starting treatment with dupilumab, an anti-interleukin-4 receptor subunit α monoclonal antibody, for bronchial asthma. Based on the lower gastrointestinal endoscopy findings, the patient was diagnosed with ulcerative colitis. Despite medication, the patient's bloody stool was not well controlled; however, the situation improved after discontinuation of dupilumab. Based on the patient's clinical course, drug-induced ulcerative colitis due to dupilumab was diagnosed. Careful monitoring of the symptoms associated with the development of enteritis is necessary after dupilumab administration.

Indexed as

Antibodies, MonoclonalAntibodies, Monoclonal, HumanizedColitis, UlcerativeInterleukin-4 Receptor alpha SubunitAdultAsthmaFemaleHumansAntibodies, MonoclonalAntibodies, Monoclonal, HumanizeddupilumabInterleukin-4 Receptor alpha Subunitbronchial asthmadupilumabinterleukin-17molecularly targeted therapyulcerative colitis

Identifiers

PMID41125370
PMCPMC13294598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.