Evidence map›Paper›PMID 41125290›Full record

ArticleBMJ open2025

Participants' experiences of potential adverse effects of an intervention to improve critical thinking about health choices: a qualitative cross-trial process evaluation in Kenya, Rwanda and Uganda.

Matt Oxman, Faith Chesire, Michael Mugisha, Ronald Ssenyonga, Allen Nsangi, Andrew D Oxman, Atle Fretheim, Sarah Rosenbaum, Margaret Kaseje, Nelson Sewankambo and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matt OxmanCentre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway matt@mattoxman.com.ORCID http://orcid.org/0000-0002-6323-9620
Faith ChesireTropical Institute of Community Health and Development, Kisumu, Kenya.
Michael MugishaInstitute of Health and Society, University of Oslo, Oslo, Norway.
Ronald SsenyongaInstitute of Health and Society, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0002-2409-3593
Allen NsangiMakerere University College of Health Sciences, Kampala, Uganda.ORCID http://orcid.org/0000-0001-8702-9217
Andrew D OxmanCentre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0002-5608-5061
Atle FretheimCentre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0002-6268-7966
Sarah RosenbaumCentre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0001-8334-7664
Margaret KasejeTropical Institute of Community Health and Development, Kisumu, Kenya.ORCID http://orcid.org/0000-0001-9789-1927
Nelson SewankamboMakerere University College of Health Sciences, Kampala, Uganda.
Monica Melby-LervågCentre for Research on Special Needs Education and Inclusion, University of Oslo Faculty of Educational Sciences, Oslo, Norway.
Simon LewinCentre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0001-7521-9515

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore participants' experiences of potential adverse effects of the Informed Health Choices secondary school intervention across three trial sites and to revise a framework of potential adverse effects of interventions to improve critical thinking about health choices.

designThis was a qualitative study. We extracted and analysed relevant data from separate process evaluations in each country. Data came from surveying teachers, observing lessons and group and individual interviews with students, teachers and other stakeholders. We modified and applied framework analysis, including five stages: (1) development of an initial framework of potential adverse effects, (2) familiarisation with the data, (3) indexing, (4) abstraction and synthesis and (5) revising the framework. We applied reflexive strategies individually and as a team.

settingLower secondary school in five randomly sampled subcounties of Kisumu County in Kenya, districts representing all five provinces in Rwanda, and six districts in the central region of Uganda, between 2022 and 2024.

participantsStudents and teachers in the intervention arms of the trials, parents of students in the intervention arms and administrators at intervention schools, as well as curriculum developers and policy-makers.

interventionThe intervention involved providing teachers with a 2-3-day training workshop, and digital classroom resources, including lesson plans for 10 lessons to be delivered over the course of one semester.

resultsWe generated findings about potential increases in adverse misunderstandings, anxiety related to transfer of learning, adversely experienced cognitive dissonance, work or schoolwork-related stress, inequity, conflicts and waste. The revised framework includes the same categories of potential adverse effects as our initial framework: decision-making harms, psychological harms, equity harms, group and social harms, waste and other harms. We revised other elements of the framework, including definitions of the categories and its structure.

conclusionsThis study provides insight into the potential adverse effects of interventions to improve critical thinking about health choices. The findings complement those of the trials and country-level process evaluations.

Indexed as

Choice BehaviorStudentsThinkingAdolescentFemaleHumansKenyaMaleQualitative ResearchRwandaSchoolsSchool TeachersUgandaHealth EducationHealth LiteracyPUBLIC HEALTHQUALITATIVE RESEARCH

Identifiers

PMID41125290
PMCPMC12548629

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.