Observational studyMovement disorders clinical practice2026
Comparative Analysis of the Incidence, Prevalence, and Survival of 8 Types of Parkinsonism in a Population-Based Study with 367 Million Person Years of Observation over 21 Years.
Observational study in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Advanced Eye Movement Features Measured by Quantitative Oculography as Candidate Biomarkers for Progressive Supranuclear Palsy.Diagnostics (Basel, Switzerland) · 2026Review
- Inhaled Levodopa for the Management of OFF Episodes in Parkinson's Disease: A Cost-Effectiveness Analysis.PharmacoEconomics · 2026Article
- One world, one goal: Advocacy and policy for a unified Parkinson's response.Journal of Parkinson's disease · 2026Review
- Early bone health assessment is indicated in Parkinson's: Risk factor analysis in a UK population-based cohort study.Journal of Parkinson's disease · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFindings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare.
objectivesTo analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug-induced parkinsonism, and other secondary parkinsonism) from 2003 to 2023, assess their survival, and define sociodemographic factors associated with PD.
methodsAnalysis of primary and linked secondary care data in a population-based UK observational study using multivariable regression models and Kaplan-Meier survival methods.
resultsAge- and sex-adjusted incidence and prevalence rates of rarer parkinsonisms increased substantially pre-Covid-19, while adjusted PD rates declined then stabilized. From 2003 to 2010, the incidence of rarer parkinsonisms increased annually by 13.8% (95% CI 13.5, 14.0%), while PD incidence declined annually by 4.7% (4.5, 4.9%). From 2011 to 2019, the incidence of rarer parkinsonisms increased annually by 3.2% (2.9, 3.5%) while PD incidence changed by -0.3% (-0.5, 0.0%) annually. Prevalence fell for PD from 2003 to 2019 by 0.6% annually (0.6, 0.7%), but increased for other parkinsonisms by 7.1% (6.8, 7.3%) before slowing to 3.3% (3.1, 3.5%) annually. Of the degenerative parkinsonisms, 5-year survival was best for PD at 64.2% (64.0, 64.4%) and worst for PSP at 30.5% (29.3, 31.8%). Adjusted PD incidence was 43% lower (16, 62%) in individuals of African/Caribbean ethnicity, but similar for Asian and White ethnicities.
conclusionsIncreasing diagnosis of rarer parkinsonisms has contributed to changing temporal trends for PD. Ethnic variations for PD justify further exploration.
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