Evidence map›Paper›PMID 41124313›Full record

ArticleAmerican journal of speech-language pathology2025

Examining Milk-Thickening Practices for Infants With Cleft Palate: A Scoping Review.

Jessica L Chee-Williams, Kelly Nett Cordero, Nancy J Scherer, Lauren L Madhoun

Abstract readScoping Review
In one paragraph

Article in American journal of speech-language pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica L Chee-WilliamsPhoenix Children's Center for Cleft and Craniofacial Care, Division of Plastic Surgery, Phoenix Children's Hospital, AZ.ORCID 0000-0002-2882-7275
Kelly Nett CorderoPhoenix Children's Center for Cleft and Craniofacial Care, Division of Plastic Surgery, Phoenix Children's Hospital, AZ.ORCID 0000-0001-9426-8638
Nancy J SchererDepartment of Speech and Hearing Science, College of Health Solutions, Arizona State University, Tempe.ORCID 0000-0001-5175-0192
Lauren L MadhounLancaster Cleft Palate Clinic, PA.

Funding

Velopharyngeal insufficiency following cleft palate repair: a comparative effectiveness study of existing surgical procedures and identification of criteria to guide a personalized treatment approachU01DE029750 · NIDCR · PHOENIX CHILDREN'S HOSPITAL · PI SITZMAN, THOMAS JAMES · 2020 to 2024
$4.2M
NIDCR NIH HHS U01 DE029750
6 · The paper itself

Abstract

purposeA common intervention to address aspiration and reflux in infants is thickening milk. However, thickening milk may further complicate feeding management for infants with cleft palate using adaptive feeding methods. The purpose of this scoping review was to identify and describe the types of milk thickener used for infants with cleft palate (with or without cleft lip) and the feeding modalities through which thickened milk is administered.

methodA comprehensive scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines. Five databases were searched: PubMed, Scopus, CINAHL, Google Scholar, and EBSCO Open Dissertations, in addition to citation searching. Records were limited to English-language publications with no date restrictions. Both peer-reviewed and gray-literature sources were included. After removing 868 duplicates, 2,282 records were screened by title and abstract. Sixty-four full-text articles were assessed for eligibility.

resultsOne study met the inclusion criteria. Milk thickening was used as an intervention for infants with isolated Pierre Robin sequence and cleft palate. The thickener used was a modified corn-based flour at approximately 3% concentration to achieve a thicker liquid consistency. The thickened milk was offered via a bottle with latex nipples of varying hole sizes (original, intermediate, and 1-mm) depending on the infant's needs. Despite only one study meeting the inclusion criteria by specifying thickener type and/or feeding modality, 11 tutorial and seminar articles that discussed milk thickening as an intervention strategy in this population were identified. However, these articles lacked any information on the type of thickener and feeding modality, and none implemented the intervention with infants.

conclusionAlthough milk thickening is described as a strategy in several tutorial and seminar articles, there is a paucity of empirical evidence to support milk thickening as a feeding intervention strategy for infants using cleft-adapted feeding methods.

Indexed as

Cleft PalateFeeding MethodsMilkCleft LipHumansInfantInfant, Newborn

Identifiers

PMID41124313
PMCPMC12611417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.