Evidence map›Paper›PMID 41124304›Full record

ReviewChemSusChem2025

Effect of Lignin, Humins, and Biomass-Derived Acids on Kinetics of Catalytic Hydroxymethylfurfural Production during Saccharide Dehydration Reactions.

Ana Jakob, Blaž Likozar, Miha Grilc

Abstract readReview
In one paragraph

Review in ChemSusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ana JakobDepartment of Catalysis and Chemical Reaction Engineering, National Institute of Chemistry, Hajdrihova 19, Ljubljana, 1000, Slovenia.
Blaž LikozarDepartment of Catalysis and Chemical Reaction Engineering, National Institute of Chemistry, Hajdrihova 19, Ljubljana, 1000, Slovenia.
Miha GrilcDepartment of Catalysis and Chemical Reaction Engineering, National Institute of Chemistry, Hajdrihova 19, Ljubljana, 1000, Slovenia.ORCID https://orcid.org/0000-0002-8255-647X

Funding

Horizon 2020 Framework Programme 887226Javna Agencija za Raziskovalno Dejavnost RS P2-0152
6 · The paper itself

Abstract

Hemicelluloses, the most prevalent components of waste lignocellulosic biomass, can be efficiently converted through the hydrolysis of polysaccharides and subsequent dehydration of individual sugar units into value-added furanics. Over the past two decades, the hydroxymethylfurfural (HMF) biobased compound has demonstrated immense potential for its utilization capacity. However, the low process efficiency of the HMF production on an industrial scale has been restricting its valorization. Experimental kinetic studies are thus useful to elucidate underlying reaction mechanisms, enabling process optimization, and assessing biorefinery techno-economic operation. This review aims to present, analyze, and examine the validated characteristic activity of homogeneously, and heterogeneously catalyzed sugar dehydration, namely glucose, fructose, and xylose, as well as real wood and agricultural streams. Kinetic studies demonstrated the trend of strong temperature sensitivity for both HMF and humin formation and feedstock-dependent selectivity. Systematic testing with complex mixtures, controlled material samples, and model chemical intermediates contributes to unraveling the impact of feedstock complexity on HMF synthesis by identifying unwanted interactions and regulating the influence of impurities. Therefore, the principles of these elusive pathways are evaluated, discussing the possibilities of limiting undesired side products. Comparing the relevance of HMF, an overview is concluded with the acknowledged challenges of feedstock, impacting HMF selectivity.

Indexed as

carbohydrate dehydrationcatalysishuminshydroxymethylfurfuralkinetic modellinglignocellulosic biomass

Identifiers

PMID41124304
PMCPMC12703454

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.