Evidence map›Paper›PMID 41124250›Full record

ArticleScience advances2025

Immunopeptidome analysis reveals SERPINB3 as an autoantigen driving eczematized psoriasis.

Manja Jargosch, Jomy Kuruvila, Emanuele Scala, Johannes Grosch, Jessica Eigemann, Sophia Wasserer, Shalva Lekiashvili, Nico Trautwein, Daniel Johannes Kowalewski, Alexander Böhner and 16 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Manja JargoschDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0000-0001-6051-4036
Jomy KuruvilaDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0009-0009-0840-6826
Emanuele ScalaDivision of Dermatology and Venereology, Department of Medicine Solna, and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-6848-3262
Johannes GroschZAUM-Center of Allergy and Environment, Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.
Jessica EigemannDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0009-0009-1363-6247
Sophia WassererDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0009-0009-2797-6867
Shalva LekiashviliDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0000-0002-3579-2824
Nico TrautweinInstitute of Immunology, University of Tübingen, Tübingen, Germany.ORCID 0000-0003-3292-8850
Daniel Johannes KowalewskiInstitute of Immunology, University of Tübingen, Tübingen, Germany.ORCID 0000-0003-0482-9927
Alexander BöhnerDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
Yigit KöseogluDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0009-0000-3762-0498
Christina HilligDepartment of Computational Health, Institute of Computational Biology, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0001-7447-547X
Jenny ThomasDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0000-0002-6386-7352
Felix LaufferDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0000-0002-1992-2836
Carsten B Schmidt-WeberZAUM-Center of Allergy and Environment, Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.ORCID 0000-0002-3203-8084
Michael P MendenDepartment of Computational Health, Institute of Computational Biology, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0003-0267-5792
Juliane S WalzInstitute of Immunology, University of Tübingen, Tübingen, Germany.ORCID 0000-0001-6404-7391
Susanne KaeslerDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
Stefanie EyerichZAUM-Center of Allergy and Environment, Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.
Simon BlankZAUM-Center of Allergy and Environment, Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.
Hans-Georg RammenseeInstitute of Immunology, University of Tübingen, Tübingen, Germany.ORCID 0000-0003-1614-2647
Tilo BiedermannDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0000-0002-5352-5105
Kilian EyerichDivision of Dermatology and Venereology, Department of Medicine Solna, and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-0094-2674
Zsuzsanna KurgyisDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0000-0002-3958-4205
Lena K FreudenmannInstitute of Immunology, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-9827-4979
Natalie Garzorz-StarkDepartment of Dermatology and Allergy, Technical University of Munich, Munich, Germany.ORCID 0000-0002-7409-7883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis (Pso) is a chronic inflammatory skin disease driven by T helper 17 (T

Indexed as

AutoantigensPsoriasisSerpinsAnimalsAntigens, NeoplasmDisease Models, AnimalFemaleHumansMiceSkinTh17 CellsTh2 CellsAntigens, NeoplasmAutoantigensSerpinssquamous cell carcinoma-related antigen

Identifiers

PMID41124250
PMCPMC12542932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.