Evidence map›Paper›PMID 41124248›Full record

ArticleScience advances2025

Visualizing the chronicle of multiple cell fates using a near-IR dual-RNA/DNA-targeting probe.

Linawati Sutrisno, Gary J Richards, Jack D Evans, Michio Matsumoto, Xianglan Li, Koichiro Uto, Jonathan P Hill, Masayasu Taki, Shigehiro Yamaguchi, Katsuhiko Ariga

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Nanoarchitectonics in Materials Science, Second Edition.Materials (Basel, Switzerland) · 2026
    Article
  5. The 15th Anniversary ofMaterials (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linawati SutrisnoInternational Center for Young Scientists (ICYS), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.ORCID 0000-0003-3085-9660
Gary J RichardsResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.ORCID 0000-0002-5262-2587
Jack D EvansSchool of Physics, Chemistry and Earth Sciences, The University of Adelaide, North Terrace, Adelaide, South Australia 5005, Australia.ORCID 0000-0001-9521-2601
Michio MatsumotoResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.ORCID 0000-0002-6037-0228
Xianglan LiBioanalysis Unit, National Institute for Materials Science, 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047, Japan.ORCID 0000-0003-0992-1722
Koichiro UtoResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.ORCID 0000-0001-7091-0585
Jonathan P HillResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.ORCID 0000-0002-4229-5842
Masayasu TakiInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo, Chikusa, Nagoya 464-8601, Japan.ORCID 0000-0003-2185-4593
Shigehiro YamaguchiInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo, Chikusa, Nagoya 464-8601, Japan.ORCID 0000-0003-0072-8969
Katsuhiko ArigaResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.ORCID 0000-0002-2445-2955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early detection and late-stage cell fate assessment are key factors to develop therapeutic strategies, although current methods cannot capture early responses or distinguish multiple injury states, especially in ultraviolet-visible (UV-vis)-sensitive cells. Here, we introduce a method to simultaneously detect variations in RNA and DNA under near-infrared photoexcitation. Using a pyrazinacene-based probe (

Indexed as

DNARNAApoptosisCellular SenescenceFluorescent DyesHumansSingle-Cell AnalysisDNAFluorescent DyesRNA

Identifiers

PMID41124248
PMCPMC12542947

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.