ArticleJACC. Case reports2025
Nitroglycerin-Induced Coronary Collapse in a Patient With Myocardial Bridging.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial bridging (MB) is a congenital anomaly in which a segment of a coronary artery, typically the left anterior descending artery (LAD), courses intramyocardially. Though often benign, MB can cause angina, ischemia, arrhythmias, or acute coronary syndromes. Nitroglycerin, a common treatment for chest pain, may paradoxically worsen MB-related ischemia by enhancing vessel compression during systole. CASE SUMMARY: A 48-year-old woman presented with chest pain and nonsustained ventricular tachycardia. Coronary computed tomography revealed a mid-LAD bridge with dynamic systolic compression. Nitroglycerin worsened stenosis to near-occlusion (99%), which improved after intracoronary nicardipine by 39%. She underwent successful unroofing and left internal mammary artery-to-LAD bypass. DISCUSSION: This case underscores the paradoxical effects of nitroglycerin in MB and the need for advanced imaging. Surgical intervention may be warranted in severe, refractory cases. Multidisciplinary management optimizes outcomes. TAKE-HOME MESSAGES: MB can precipitate ischemia. Nitroglycerin may worsen systolic compression, leading to coronary collapse; prompt diagnosis is critical to achieve optimal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.