Evidence map›Paper›PMID 41123396›Full record

SynthesisOncology nursing forum2025

Hematopoietic Stem Cell Transplantation and Psychosocial Impacts on Sibling Donors of Pediatric Patients: A Systematic Review of Qualitative Studies.

Ibrahim Alananzeh, Heidi Green, Amir Masoud Sharifnia, Samaneh Alinejad Mofrad, Ritin Fernandez

Abstract readSystematic Review
In one paragraph

Synthesis in Oncology nursing forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ibrahim AlananzehIbrahim Alananzeh.
Heidi GreenHeidi Green.
Amir Masoud SharifniaAmir Masoud Sharifnia.
Samaneh Alinejad MofradSamaneh Alinejad Mofrad.
Ritin FernandezRitin Fernandez.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

problem identificationHematopoietic stem cell transplantation has significant psychosocial impacts on pediatric sibling donors, including emotional distress, guilt, and anxiety. The aim of this qualitative review is to explore their experiences and the challenges they face. LITERATURE SEARCH: A systematic review of qualitative studies of sibling donors was conducted using JBI guidelines. A search of MEDLINE®, Scopus®, CINAHL®, PsycINFO®, and ProQuest identified nine qualitative studies involving 70 sibling donors. DATA EVALUATION: Studies were critically appraised using JBI methodology for systematic reviews of qualitative evidence. Data were synthesized to understand psychosocial experiences of sibling donors. SYNTHESIS: The following four main themes emerged: (a) Sibling donors felt trapped and experienced mixed emotions about donating, (b) family life was significantly disrupted after the sibling's illness, (c) donors developed a sense of pride from being able to help their sibling, and (d) the donation process required better emotional support for the donors. IMPLICATIONS FOR PRACTICE: Pediatric healthcare professionals should offer specialized psychosocial support to sibling donors. Additional qualitative research is needed to assess the long-term psychosocial effects on these donors.

Indexed as

Hematopoietic Stem Cell TransplantationSiblingsTissue DonorsAdolescentAdultChildChild, PreschoolFemaleHumansInfantMaleMiddle AgedQualitative Researchhematopoietic stem cell transplantationpsychosocialqualitative researchsystematic review

Identifiers

PMID41123396
PMCPMC12549063

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.