Observational studyActa dermato-venereologica2025
Characterization of Contact Urticaria Syndrome Phenotypes: A Retrospective Study of 95 Cases.
Observational study in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Update on occupational contact urticaria: a systematic narrative review.Current opinion in allergy and clinical immunology · 2026Pooled it
- Occupational Contact Urticaria, Protein Contact Dermatitis and Concomitant Airway Diseases in the Finnish Register of Occupational Diseases in 2005-2020: Main Causes and Occupations at Risk.Contact dermatitis · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contact urticaria syndrome, encompassing immunological contact urticaria and protein contact dermatitis, comprises immediate cutaneous reactions with potential systemic manifestations, including anaphylaxis. These conditions are frequently underdiagnosed despite their significant occupational impact. This study aimed to evaluate the clinical and laboratory features associated with distinct phenotypes of contact urticaria syndrome. A retrospective, observational analysis was performed at Hospital del Mar (Barcelona) from January 2010 to January 2024, including adult patients diagnosed with immunological contact urticaria and/or protein contact dermatitis and a positive prick test. Demographic data, clinical data, and complementary test results, including culprit agents, were compared between patients with isolated contact urticaria and those with protein contact dermatitis. A total of 95 patients were included. Results indicated that isolated contact urticaria was more frequently associated with facial involvement (n = 19, 28.8%) and a higher rate of systemic reactions (n = 18, 27.3%), including anaphylaxis, whereas protein contact dermatitis was frequently occupational-related (n = 19, 65.5%), and with a trend toward higher atopic dermatitis comorbidity (n = 12, 41.4%). These findings emphasize the heterogeneity of contact urticaria syndrome and underscore the importance of comprehensive clinical evaluation for effective diagnosis and management.
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Registered trials
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