ArticleBone & joint research2025
Transcutaneous carbon dioxide improves joint inflammation and articular cartilage degeneration in rat osteoarthritis models.
Article in Bone & joint research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Inhibition of Cathepsin C attenuates osteoarthritis by modulating macrophage activated status and reducing tissue inflammatory responses.Bone & joint research · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
Aims: As global ageing and life expectancy increase, the prevalence and incidence of osteoarthritis (OA) are expected to rise. Transcutaneous carbon dioxide (CO Methods: OA model was induced in 32 nine-week-old male Wistar rats by intra-articular injection of monosodium iodoacetate (MIA) and surgically induced by destabilization of the medial meniscus (DMM) in the knee joint. The pathogenesis period of MIA was set at two weeks, and for DMM at four weeks. After the creation of the OA model, either CO Results: Assessments of knee joint diameter showed that knee swelling in the DMM model improved significantly after two weeks of CO Conclusion: Our results demonstrate that transcutaneous CO
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Registered trials
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