ReviewJournal of dental research2026
Single-Cell Analysis of Fibroblast Subpopulations in Skin and Oral Mucosa.
Review in Journal of dental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Beyond the clot: how the biomolecular landscape of platelet-rich fibrin directs fibroblast functions.Frontiers in oral health · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Fibroblasts are the principal mesenchymal cell type found within the connective tissues of all organs. Once thought to play a passive role in tissue remodeling, fibroblasts have now emerged as a key player in regulating structural immunity and modulating the reparative injury response. A recent surge in single-cell RNA sequencing studies has advanced our understanding of the biology of fibroblasts, highlighting their cellular diversity and organization across health and diseased conditions at an unprecedented resolution. In this review, we discuss up-to-date literature on fibroblast subpopulations identified from 2 distinct barrier tissues: oral mucosa and skin. We focus on the transcriptomic signatures that distinguish subsets of fibroblasts in homeostasis and perturbed conditions (i.e., wound healing or chronic inflammatory diseases), and we link them to mechanistic studies that provide functional insights. A deeper understanding of fibroblast diversity and its functional significance may uncover tissue-specific roles in regeneration and immunomodulation, which will be crucial for the development of precision therapy that directly targets fibroblast subsets.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.