Evidence map›Paper›PMID 41122942›Full record

ArticleJournal of psychopharmacology (Oxford, England)2026

Self-treatment of psychiatric conditions using ketamine: Patterns, characteristics, and retrospective insights.

Gabrielle Smith, Timothy Piatkowski, Jason Ferris, Benjamin Bonenti, Emma Davies, Monica J Barratt, Celia Morgan, Adam Winstock, Cheneal Puljević

Abstract read
In one paragraph

Article in Journal of psychopharmacology (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gabrielle SmithSchool of Public Health, The University of Queensland, Brisbane, QLD, Australia.
Timothy PiatkowskiSchool of Applied Psychology and Centre for Mental Health, Griffith University, Brisbane, QLD, Australia.ORCID 0000-0002-6177-0266
Jason FerrisCentre for Health Services Research, The University of Queensland, Brisbane, QLD, Australia.ORCID 0000-0001-7474-0173
Benjamin BonentiSchool of Applied Psychology and Centre for Mental Health, Griffith University, Brisbane, QLD, Australia.
Emma DaviesCentre for Psychological Research, Oxford Brookes University, UK.
Monica J BarrattSocial Equity Research Centre and Digital Ethnography Research Centre, RMIT University, Melbourne, VIC, Australia.
Celia MorganDepartment of Psychology, University of Exeter, UK.
Adam WinstockUniversity College London, UK.
Cheneal PuljevićSchool of Public Health, The University of Queensland, Brisbane, QLD, Australia.ORCID 0000-0002-3658-9772

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile research on novel therapeutic applications of ketamine is expanding, particularly in controlled settings, there is limited exploration of its consumption related to self-treatment of psychiatric conditions. This study investigated the characteristics of people who use ketamine and psychedelics for self-treatment of psychiatric conditions, providing insight into patterns of use within this population.

methodsUtilising the 2020 Global Drug Survey, the analysis incorporates data from 5831 respondents who reported self-treating with unregulated drugs to treat diagnosed psychiatric conditions. We compare three groups: those self-treating with only ketamine (

resultsA high proportion (>60%) had prior psychiatric diagnoses, with depression and anxiety being the most common. People who used both ketamine and other substances reported higher festival and clubbing attendance than the other two groups. People who used ketamine and combined it with other psychedelics used it more frequently (incidence rate ratio (IRR): 0.729, 95% confidence interval (CI): 0.336-1.581), while those using non-ketamine psychedelics only showed a significant reduction in ketamine usage volume (IRR: 0.160, 95% CI: 0.079-0.322) compared to other groups. Almost half of the respondents sought online advice before starting ketamine self-treatment.

conclusionThis study extends knowledge about various populations using ketamine for self-treatment purposes, proposes areas for future research and suggests online platforms as the most effective place for harm reduction resources relating to ketamine use.

Indexed as

HallucinogensKetamineMental DisordersAdolescentAdultFemaleHumansMaleMiddle AgedRecreational Drug UseRetrospective StudiesSelf MedicationSubstance-Related DisordersSurveys and QuestionnairesYoung AdultHallucinogensKetaminedrugsharm reductionketaminemental healthself-treatment

Identifiers

PMID41122942
PMCPMC13351112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.