ArticleAnnals of medicine2025
Redefining surgical boundaries: outcomes of minimally invasive adrenalectomy in large pheochromocytomas.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
backgroundThe safety and efficacy of minimally invasive adrenalectomy (MIA) for large pheochromocytoma (PHEO) remains a hotly debated topic. This study aims to shed light on the feasibility and safety of MIA for PHEOs > 5 cm. MATERIALS AND
methodsWe conducted a comprehensive retrospective analysis of 135 patients who underwent MIA for PHEOs at our centre from January 2016 to February 2023. After propensity score-matching (PSM) to balance baseline variables, 91 patients with tumours ≤ 5 cm and 44 patients with tumours > 5 cm were grouped into 33 pairs. Patient demographics and perioperative data were meticulously recorded and compared.
resultsAfter PSM, 33 pairs of patients were included (the larger group: 13 males, 20 females; mean age 50.0 ± 14.8 years; the smaller group: 12 males, 21 females; mean age 53.7 ± 11.8 years). There was no significant difference in baseline characteristics between the two groups except for tumour size (6.4 vs. 3.4 cm,
conclusionsAlthough MIA for PHEOs > 5 cm had longer operative time and drainage tube removal time, it did not affect intraoperative hemodynamic outcomes and perioperative complications. Thus, minimally invasive adrenalectomy represents a viable and effective surgical option for managing large PHEO.
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