Evidence map›Paper›PMID 41122788›Full record

ArticleJournal of the International Neuropsychological Society : JINS2025

Pre-injury sleep disturbance as a moderator of cognitive functioning in children and adolescents with mild traumatic brain injury.

Caroline A Luszawski, Nori M Minich, H Gerry Taylor, Erin D Bigler, Ann Bacevice, Barbara A Bangert, Daniel M Cohen, Nicholas A Zumberge, Keith Owen Yeates

Abstract read
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In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caroline A LuszawskiDepartment of Psychology, https://ror.org/03yjb2x39University of Calgary, Calgary, AB, Canada.ORCID 0009-0000-5766-6813
Nori M MinichDepartment of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
H Gerry TaylorDepartment of Pediatrics, The Ohio State University, Columbus, OH, USA.ORCID 0000-0001-9035-0853
Erin D BiglerDepartment of Psychology and Neuroscience, Brigham Young University, Provo, UT, USA.
Ann BaceviceDepartment of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
Barbara A BangertDepartment of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
Daniel M CohenDepartment of Pediatrics, The Ohio State University, Columbus, OH, USA.
Nicholas A ZumbergeDepartment of Pediatrics, The Ohio State University, Columbus, OH, USA.
Keith Owen YeatesDepartment of Psychology, https://ror.org/03yjb2x39University of Calgary, Calgary, AB, Canada.

Funding

Predicting Outcomes in Children with Mild Traumatic Brain InjuryR01HD076885 · NICHD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI YEATES, KEITH O · 2013 to 2018
$3.0M
NICHD NIH HHS R01 HD076885
6 · The paper itself

Abstract

objectiveHealthy sleep contributes to better cognitive functioning in children. This study sought to investigate the role of pre-injury sleep disturbance as a predictor or moderator of cognitive functioning across 6 months post-injury in children with mild traumatic brain injury (mTBI) or orthopedic injury (OI).

methodParticipants were 143 children with mTBI and 74 with OI, aged 8 - 16 years, prospectively recruited from the Emergency Departments of two children's hospitals in Ohio, USA. Parents rated their children's pre-injury sleep retrospectively using the Sleep Disorders Inventory for Students. Children completed the National Institutes of Health (NIH) Toolbox Cognition Battery at 10 days and 3 and 6 months post-injury.

resultsGroup differences in both overall performance and reaction time on the Flanker Inhibitory Control and Attention Test varied significantly as a function of the level of pre-injury sleep disturbance as well as time since injury. At the 10 day visit, among children with worse pre-injury sleep, mTBI was associated with slower reaction times relative to OI. Among children with worse pre-injury sleep, those with mTBI improved over time while those with OI did not. Main effects of pre-injury sleep and time since injury were found for several other NIH Toolbox subtests, with poorer performance associated with worse pre-injury sleep and early vs. later timepoints.

conclusionsThese results suggest that pre-existing sleep disturbances and mTBI are jointly associated with poorer executive functioning post-injury. Interventions to improve sleep might help mitigate the effects of mTBI on children's cognitive functioning.

Indexed as

Brain ConcussionCognitive DysfunctionSleep Wake DisordersAdolescentChildExecutive FunctionFemaleHumansMaleNeuropsychological TestsProspective StudiesReaction Timechildcognitionconcussionmild traumatic brain injuryPediatricsleep

Identifiers

PMID41122788
PMCPMC13183342

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.