Evidence map›Paper›PMID 41122713›Full record

ReviewFrontiers in endocrinology2025

Malignant melanoma with pituitary metastasis: A case report and literature review.

Xiaoling Li, Wenhui Jiang, Xiaohui Tang, Meiying Chen, Wenhua Deng, Yunyu Wang, Xingfu Wang

Abstract readCase ReportsReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoling LiDepartment of Pathology, The Second Hospital of Longyan, Longyan, China.
Wenhui JiangDepartment of Pathology, The Second Hospital of Longyan, Longyan, China.
Xiaohui TangDepartment of Pathology, The Second Hospital of Longyan, Longyan, China.
Meiying ChenMolecular Biology Laboratory, The Second Hospital of Longyan, Longyan, China.
Wenhua DengMolecular Biology Laboratory, The Second Hospital of Longyan, Longyan, China.
Yunyu WangDepartment of Pathology, The Second Hospital of Longyan, Longyan, China.
Xingfu WangDepartment of Pathology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Pituitary metastasis of malignant melanoma (MM) is rare. This study aimed to explore its diagnostic features using a multimodal approach and retrospectively analyzed previously reported cases to summarize its pathogenesis and diagnostic challenges. Methods: We screened all published case reports and case series on pituitary metastatic MM using PubMed, focusing on cases with detailed clinical data, imaging features, pathological examination, and molecular test results. A total of 24 cases of MM with pituitary metastasis, including our case, were retrospectively analyzed. Additionally, the index patient underwent histopathological, immunohistochemical (S100, SOX10, Melan-A, HMB-45, Results: This case involved a 65-year-old female patient whose pathological examination revealed tumor cells with epithelioid and spindle cell features. Immunohistochemical analysis showed diffuse positivity for S-100, vimentin, and Conclusion: Diagnosing MM with pituitary metastasis requires integrating detailed clinical history, imaging features, pathological examination, and molecular testing. Our findings highlight the importance of a comprehensive diagnostic approach with multidisciplinary collaboration when managing atypical pituitary masses, along with detailed investigation of a patient's previous tumor history, to improve diagnostic accuracy and patient outcomes.

Indexed as

MelanomaPituitary NeoplasmsSkin NeoplasmsAgedFemaleHumansMaleMutationProto-Oncogene Proteins B-rafBRAF protein, humanProto-Oncogene Proteins B-rafBRAF V600Ecase reportmalignant melanomamultimodal diagnosispituitary metastasis

Identifiers

PMID41122713
PMCPMC12535866

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.