Evidence map›Paper›PMID 41122625›Full record

ArticleCureus2025

Evaluation of the Effect of Commiphora wightii and Asthiposhak in Experimental Rat Model of Osteoarthritis.

Achal A Sukhdeve, Yashashri C Shetty, Mukesh Chawda, Megha Nalawade, Minakshi Dongre

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Achal A SukhdevePharmacology and Therapeutics, Seth G S Medical College and KEM Hospital, Mumbai, IND.
Yashashri C ShettyPharmacology and Therapeutics, Seth G S Medical College and KEM Hospital, Mumbai, IND.
Mukesh ChawdaMedical Services, Solumiks Herbaceuticals Limited, Mumbai, IND.
Megha NalawadeClinical Research Associate, Shree Dhootapapeshwar Limited, Mumbai, IND.
Minakshi DongrePharmacology and Therapeutics, Seth G S Medical College and KEM Hospital, Mumbai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Western medicine, a lot of research is ongoing to find molecules for osteoarthritis (OA). Ayurvedic physicians have tried METHODOLOGY: After (Institutional Animal Ethics Committee (IAEC)/GSMC/02/2023) animal ethics approval, seven groups (n=6, each group): Normal Control, Disease Control, Positive Control,

resultsIn the behavioural test, rotarod and hot plate analgesiometer, it was found that CW, both doses, and ASTP-HD have shown good improvement in comparison to disease control. While in the grip strength and open field test, CW, both doses have shown significant improvement. In histopathology, CW

conclusionCW both doses and ASTP high dose exhibited antiarthritic effect by virtue of its effects on behavioural tests, histology scores, and chondroprotective biomarkers.

Indexed as

antiarthriticcartilage oligomeric matrix protein (comp)chondroprotectivegrip strength testmatrix metalloproteinase-13 (mmp-13)

Identifiers

PMID41122625
PMCPMC12536813

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.