ArticleFrontiers in medicine2025
The effect of esketamine on perioperative neurocognitive dysfunction in elderly patients undergoing gastrointestinal tumor surgery: a randomized double-blind controlled study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Neuroinflammation in postoperative cognitive dysfunction: the multi-target potential of esketamine in modulating microglial responses and synaptic integrity.Frontiers in molecular neuroscience · 2026Review
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Authors and funding
5 authors.
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Abstract
Background: We aimed to whether esketamine induction and maintenance of general anesthesia could reduce the incidence of perioperative neurocognitive dysfunction (PND) in elderly patients undergoing gastrointestinal tumor surgery and explore the related mechanisms preliminarily. Patients and methods: A total of 153 elderly patients were divided into two groups: a control group (group C, Results: The incidence of PND in group K at 7 days after surgery was lower than that in group C ( Conclusion: The use of esketamine for anesthesia induction and maintenance in elderly patients undergoing gastrointestinal tumor surgery inhibited inflammation, alleviated neuronal injury and degeneration, improved postoperative sleep quality and cognitive function, and reduced the incidence of PND.
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