Evidence map›Paper›PMID 41122442›Full record

ReviewJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2025

Epigenetic alterations in

Camilia Metadea Aji Savitri, Lita Diah Rahmawati, Awalia, Pradana Zaky Romadhon, Langgeng Agung Waskito, Amal Arifi Hidayat, Yudith Annisa Ayu Rezkitha, Muhammad Miftahussurur, Yoshio Yamaoka

Abstract readReview
In one paragraph

Review in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Integrating multi-omics data for next-generation cancer research and precision medicine.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  3. Observational Study of the Association Between OralJournal of clinical medicine · 2026
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Camilia Metadea Aji SavitriHelicobacter Pylori and Microbiota Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, East Java, Indonesia.
Lita Diah RahmawatiDivision of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.
AwaliaDivision of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.
Pradana Zaky RomadhonDivision of Hematology and Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.
Langgeng Agung WaskitoHelicobacter Pylori and Microbiota Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, East Java, Indonesia.
Amal Arifi HidayatDepartment of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.
Yudith Annisa Ayu RezkithaHelicobacter Pylori and Microbiota Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, East Java, Indonesia.
Muhammad MiftahussururHelicobacter Pylori and Microbiota Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, East Java, Indonesia.
Yoshio YamaokaDivision of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gastric cancer (GC) is one of the top causes of cancer death worldwide, with 98% caused by Materials and Methods: A comprehensive search of PubMed and Scopus was performed for publications from 2017 to August 2022. Studies involving GC regardless of type and location, Results: A final analysis includes 26 manuscripts, comprising 10 reviews and 16 original articles. Methylation levels in various gene promoters having a role in host defense, cell integrity and cell cycle, DNA repair, and apoptosis were altered in Conclusion: Understanding the exact mechanism leading to carcinogenesis is required for GC early diagnosis and precise therapy to alleviate the disease burden.

Indexed as

Helicobacter pylorihistoneinfectious diseasemicroRNAsvirulence

Identifiers

PMID41122442
PMCPMC12536862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.