Evidence map›Paper›PMID 41122440›Full record

ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2025

Temporal evolution of electrocardiographic anomalies observed in a young woman after COVID-19 vaccine.

Elpidio Santillo, Lucio Cardinali, Luciano Marini

Abstract readCase Reports
In one paragraph

Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elpidio SantilloDepartment of Geriatric-Rehabilitative, Cardiac Rehabilitation Unit, IRCCS-INRCA, Fermo, Italy.
Lucio CardinaliDepartment of Geriatric-Rehabilitative, Cardiac Rehabilitation Unit, IRCCS-INRCA, Fermo, Italy.
Luciano MariniDepartment of Geriatric-Rehabilitative, Cardiac Rehabilitation Unit, IRCCS-INRCA, Fermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrocardiographic alterations of ventricular repolarization have already been reported in cases of myocarditis following coronavirus disease-19 (COVID-19) vaccine, but it is not clear how long they persist. A 21-year-old female presented with chest discomfort and diffuse myalgia a week after receiving the first dose of a messenger RNA (mRNA) COVID-19 vaccine. The 12 leads standard electrocardiogram unveiled negative T waves in anterior and inferior leads, while her troponin-I values resulted in the upper limit. A mild form of post-COVID-19 vaccine myocarditis was diagnosed since the echocardiogram excluded major systolic alterations and pericardial effusions. The patient refused hospitalization, but luckily, she remained hemodynamically stable, presenting a quick clinical response to oral non-steroidal anti-inflammatory therapy. However, the electrocardiographic abnormalities required weeks for resolving. In our case, the later normalization of electrocardiographic anomalies was not associated with an ominous clinical course.

Indexed as

COVID-19 vaccineselectrocardiographymyocarditis

Identifiers

PMID41122440
PMCPMC12536859

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.