Evidence map›Paper›PMID 41122325›Full record

ArticleActa naturae

p2rx3 Knockout Mice Have Altered Energy Metabolism in Hippocampal Neurons.

A S Zelentsova, M V Pokrovskii, E A Patrakhanov, V S Shmigerova, M Yu Skorkina, A V Deykin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A S ZelentsovaBelgorod State National Research University, Belgorod, 308015 Russia.
M V PokrovskiiBelgorod State National Research University, Belgorod, 308015 Russia.
E A PatrakhanovBelgorod State National Research University, Belgorod, 308015 Russia.
V S ShmigerovaBelgorod State National Research University, Belgorod, 308015 Russia.
M Yu SkorkinaBelgorod State National Research University, Belgorod, 308015 Russia.
A V DeykinBelgorod State National Research University, Belgorod, 308015 Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hippocampus is a key component of the brain that is associated with the formation of longterm memory, the energy metabolism of neurons playing a pivotal role in its mechanisms. The P2X3 receptor in the hippocampus is considered an attractive target when searching for novel biologically active substances that could work to reduce anxiety, epileptic conditions, and improve cognitive functions. In this work, the intensity of mitochondrial respiration, the glycolytic capacity, and the energy phenotype of hippocampal neurons were studied in

Indexed as

hippocampusmitochondrial respirationp2rx3 geneprimary mixed neuronal culture

Identifiers

PMID41122325
PMCPMC12536983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.