Evidence map›Paper›PMID 41122203›Full record

ArticleCase reports in infectious diseases2025

Yellow Fever Vaccine-Associated Viscerotropic Disease: A Unique Case of Atraumatic Splenic Rupture.

Eadbert Nortey, Edmund M Bediako, Geraldine K Mould, Abigail Mills-Annoh, Kwame Ekremet, Priscilla Kyei-Baffour, Ama Ekem, Jemima C A Clarke, Eugene F E K Apaloo, Susan Quartey-Papafio

Abstract readCase Reports
In one paragraph

Article in Case reports in infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Review on Yellow Fever Vaccine and Adverse Events.Global health, epidemiology and genomics · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eadbert NorteyEmergency Department, University of Ghana Medical Centre, Accra, Ghana.
Edmund M BediakoEmergency Department, University of Ghana Medical Centre, Accra, Ghana.ORCID https://orcid.org/0009-0009-6469-0286
Geraldine K MouldEmergency Department, University of Ghana Medical Centre, Accra, Ghana.ORCID https://orcid.org/0009-0007-3024-067X
Abigail Mills-AnnohEmergency Department, University of Ghana Medical Centre, Accra, Ghana.
Kwame EkremetEmergency Department, University of Ghana Medical Centre, Accra, Ghana.
Priscilla Kyei-BaffourEmergency Department, University of Ghana Medical Centre, Accra, Ghana.
Ama EkemEmergency Department, University of Ghana Medical Centre, Accra, Ghana.
Jemima C A ClarkeEmergency Department, University of Ghana Medical Centre, Accra, Ghana.
Eugene F E K ApalooEmergency Department, University of Ghana Medical Centre, Accra, Ghana.
Susan Quartey-PapafioEmergency Department, University of Ghana Medical Centre, Accra, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atraumatic splenic rupture is an uncommon, life-threatening abdominal emergency involving the rupture of the spleen in the absence of obvious trauma. This case report provides a summary of a 48-year-old male who presented to the Emergency Department of the University of Ghana Medical Centre with syncope and hemodynamic instability one week after receiving a yellow fever vaccine. A diagnosis of an atraumatic splenic rupture was eventually confirmed by imaging, and a splenectomy was done. This report aims to provide valuable insights into the recognition and management of atraumatic splenic rupture, a potential adverse event associated with the yellow-fever vaccine. It also highlights the importance of prompt diagnosis and timely intervention in such life-threatening cases.

Indexed as

abdominal painsplenic rupturevaccineviscerotropic diseaseyellow fever

Identifiers

PMID41122203
PMCPMC12537244

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.