Evidence map›Paper›PMID 41122087›Full record

ArticleGlobal advances in integrative medicine and health

Ameliorative Effects of Triphala Supplementation on Oxidative Stress and Inflammation in Individuals with Post-COVID-19 Condition: A Preliminary Randomized Controlled Trial.

Suwipa Intakhiao, Nattaphol Prakobkaew, Surachat Buddhisa, Orachorn Boonla, Yothin Teethaisong, Sukrisd Koowattanatianchai, Piyapong Prasertsri

Abstract read
In one paragraph

Article in Global advances in integrative medicine and health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Synergistic Effects of High-Intensity Interval Training andInternational journal of molecular sciences · 2025
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suwipa IntakhiaoFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand.
Nattaphol PrakobkaewFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand.
Surachat BuddhisaFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand.
Orachorn BoonlaFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand.
Yothin TeethaisongFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand.
Sukrisd KoowattanatianchaiDivision of Cardiology, Department of Medicine, Burapha Hospital, Burapha University, Chonburi, Thailand.
Piyapong PrasertsriFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand.ORCID https://orcid.org/0000-0003-2652-4622

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Triphala, a classical polyherbal formulation in Ayurvedic medicine, has traditionally been used for its diverse therapeutic properties, particularly its antioxidant, anti-inflammatory, and immunomodulatory effects. Objective: This study aimed to evaluate changes in oxidative stress, antioxidant activity, and systemic inflammation following Triphala supplementation in individuals with post-COVID-19 condition. Methods: Seventy-four participants (aged 18-53 years) with a history of COVID-19 were enrolled in a preliminary randomized, double-blind, placebo-controlled trial. Participants were randomly assigned to receive either placebo (n = 37) or Triphala (1000 mg/day; n = 37) capsules, taken 5 days per week for 8 weeks. Biomarkers assessed included malondialdehyde (MDA), protein carbonyl, superoxide dismutase (SOD), interferon-gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α), measured before and after supplementation. Results: In the Triphala group, MDA ( Conclusion: Triphala supplementation may help reduce oxidative stress and systemic inflammation in individuals with post-COVID-19 condition. Future studies with higher doses or longer treatment durations are recommended to confirm and extend these findings.

Indexed as

COVID-19herbinflammationoxidative stresstraditional medicine

Identifiers

PMID41122087
PMCPMC12536147

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.