Evidence map›Paper›PMID 41121966›Full record

ArticleJournal of hospital medicine2026

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada.

Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN)

Abstract read
In one paragraph

Article in Journal of hospital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erin HesseyThe Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0009-0003-8485-3480
Thaksha ThavamChild Health Evaluative Sciences, SickKids Research Institute, Toronto, Ontario, Canada.
Sanjay MahantThe Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-0487-5835
Eyal CohenThe Hospital for Sick Children, Toronto, Ontario, Canada.
Jingqin ZhuChild Health Evaluative Sciences, SickKids Research Institute, Toronto, Ontario, Canada.
Francine BuchananThe Hospital for Sick Children, Toronto, Ontario, Canada.
Teresa ToThe Hospital for Sick Children, Toronto, Ontario, Canada.
Peter J GillThe Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-6253-1312
Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN)

Funding

Physicians' Services Incorporated (PSI) Foundation Grant Number: 21-01. This study was also supported by ICES, which is funded by an annual grant from the Ontario Ministry of Health (MOH) and the Ministry of Long-Term Care (MLTC)
6 · The paper itself

Abstract

BACKGROUND AND

objectivesChildren with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%-5% of the pediatric population. In Canada, their care accounts for one-third of pediatric health spending. We aim to describe the most costly and prevalent conditions leading to hospitalization in CMC in Ontario, Canada.

methodsPopulation-based, cross-sectional study from a universally funded system utilizing health administrative databases. Children (<18 years old) with valid provincial healthcare coverage admitted to a hospital from 2014 to 2019 were included. CMC was defined using validated algorithms. Encounters were classified into clinical conditions using the Pediatric Clinical Classification System. Outcomes included condition-specific prevalence, cost, and cost rank estimated using a costing algorithm in Canadian dollars.

resultsThere were 627,314 pediatric hospitalizations, costing $4.28 billion. Of these, 141,653 (23%) hospitalizations were for CMC, costing $2.25 billion (52%). Among encounters for CMC, 84,280 (60%) were for children with medical technology. One-third of hospitalizations in CMC were in community hospitals. Nearly half (1.30 million, 46%) of days in hospital were in CMC, along with 60% of intensive care unit (ICU) days (667,497 days). Low birth weight ($555.4 million), prematurity ($70.0 million), and respiratory distress of the newborn ($46.6 million) were the costliest conditions. Low birth weight (88 per 1000 encounters), chemotherapy (42 per 1000 encounters), and pneumonia (29 per 1000 encounters) were the most prevalent conditions.

conclusionsUnderstanding the most costly and prevalent inpatient conditions in CMC will help to prioritize more targeted research questions and interventions to improve healthcare utilization and patient outcomes.

Indexed as

Health Care CostsHospitalizationAdolescentChildChild, PreschoolChronic DiseaseCross-Sectional StudiesFemaleHumansInfantInfant, NewbornMaleOntarioPrevalence

Identifiers

PMID41121966
PMCPMC13136918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.