Evidence map›Paper›PMID 41121722›Full record

ArticleYeast (Chichester, England)2025

Decoding the Genome of the Komagataella phaffii Type Strain CBS 2612.

Nadine Elpida Tatto, Lina Heistinger, Corinna Rebnegger, Minoska Valli, Diethard Mattanovich, Brigitte Gasser, Alexandra B Graf

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Yeast (Chichester, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nadine Elpida TattoDepartment of Biotechnology and Food Science, Institute of Microbiology and Microbial Biotechnology, BOKU University, Vienna, Austria.ORCID 0000-0002-6989-6744
Lina HeistingerDepartment of Biotechnology and Food Science, Institute of Microbiology and Microbial Biotechnology, BOKU University, Vienna, Austria.ORCID 0000-0002-0935-4652
Corinna RebneggerDepartment of Biotechnology and Food Science, Institute of Microbiology and Microbial Biotechnology, BOKU University, Vienna, Austria.
Minoska ValliDepartment of Biotechnology and Food Science, Institute of Microbiology and Microbial Biotechnology, BOKU University, Vienna, Austria.
Diethard MattanovichDepartment of Biotechnology and Food Science, Institute of Microbiology and Microbial Biotechnology, BOKU University, Vienna, Austria.ORCID 0000-0002-0907-4167
Brigitte GasserDepartment of Biotechnology and Food Science, Institute of Microbiology and Microbial Biotechnology, BOKU University, Vienna, Austria.ORCID 0000-0003-2881-6370
Alexandra B GrafDepartment of Applied Life Sciences, University of Applied Sciences Hochschule Campus Wien, Vienna, Austria.ORCID 0000-0002-2738-3270

Funding

This work was funded by the Austrian Federal Ministry of Economy, Energy and Tourism (BMWET), the Austrian Federal Ministry of Innovation, Mobility and Infrastructure (BMIMI), the Styrian Business Promotion Agency SFG, the Standortagentur Tirol, the Government of Lower Austria, the Business Agency Vienna and BOKU through the COMET Funding Program managed by the Austrian Research Promotion Agency FFG. Further support was obtained by the BMWET and the Nationalstiftung FTE through the Christian Doppler Research Association. Open access funding is provided by BOKU University.
6 · The paper itself

Abstract

The methylotrophic yeast Komagataella phaffii (formerly known as Pichia pastoris) is an essential host for biotechnological production. Here, we present the complete and annotated genome sequence of CBS 2612 T = NRRL Y-7556T, the type strain of K. phaffii. CBS 2612 has a genome length of 9,387,549 bp with 5412 predicted and 5389 annotated genes, of which 144 are tRNA genes including the previously missing tRNAs for tryptophan, tyrosine, and serine, and 34 rRNA genes. In total, 4 SNPs were found compared to the biotechnologically most commonly used strain, CBS 7435. Additionally, 34 lncRNA candidates could be identified, including candidates that affect telomere-regulation and flocculin genes.

Indexed as

Genome, FungalSaccharomycetalesMolecular Sequence AnnotationPolymorphism, Single NucleotideRNA, Long NoncodingRNA, TransferRNA, Long NoncodingRNA, TransferCBS 2612genome annotationKomagataella phaffiilong non‐coding RNAPichia pastoristRNA genes

Identifiers

PMID41121722
PMCPMC12587029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.