Evidence map›Paper›PMID 41121517›Full record

ArticleAnti-cancer agents in medicinal chemistry2026

Camel Milk in Skin Cancer Therapeutics: An

Neha Jain, Lavina Bagoria, Sneha Keelka, Prachi Jain, Renu Khandelwal, Anil Kumar Sharma, Mukesh Kumar Sharma, Pallavi Kaushik

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Article in Anti-cancer agents in medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Neha JainDepartment of Zoology, University of Rajasthan, Jaipur, 302004, India.ORCID 0009-0001-9556-0670
Lavina BagoriaDepartment of Zoology, University of Rajasthan, Jaipur, 302004, India.ORCID 0000-0002-8460-7875
Sneha KeelkaDepartment of Zoology, University of Rajasthan, Jaipur, 302004, India.ORCID 0009-0003-7996-9577
Prachi JainDepartment of Zoology, University of Rajasthan, Jaipur, 302004, India.ORCID 0009-0003-7082-913X
Renu KhandelwalDepartment of Zoology, University of Rajasthan, Jaipur, 302004, India.ORCID 0009-0008-8326-7398
Anil Kumar SharmaDepartment of Zoology, University of Rajasthan, Jaipur, 302004, India.ORCID 0009-0000-0695-6386
Mukesh Kumar SharmaDepartment of Zoology, S.P.C. Government College (M.D.S.U.), Ajmer, 305001, India.ORCID 0000-0001-8056-4591
Pallavi KaushikDepartment of Zoology, University of Rajasthan, Jaipur, 302004, India.ORCID 0000-0003-3566-1418

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTherapeutic applications of camel milk in various human ailments have led to the investigation of camel milk against multiple cancers. However, the absence of its scientific evidence in skin cancer protection has prompted this new study's inception.

methodsThe study includes estimation of camel milk's chemo-preventive potential on A431 cells and a twostage skin carcinogenesis model (Mus musculus). The in-vitro studies included MTT, scratch and flow cytometry assay to determine the anti-proliferative effects, anti-migratory ability and cell numbers in various cell cycle stages. In the in-vivo study, estimations of tumour morphology, biochemical alterations, along with a histopathological study were performed. Further, the milk was assessed for its anti-oxidative activities, followed by GCMS analysis for the investigation of potential compounds.

resultsThe in-vitro results demonstrated camel milk's dose-dependent anti-proliferation, significant (p<0.001) cell migration inhibition, and conclusive G1/S phase cell cycle arrest. The in-vivo study revealed a notable reduction in tumour parameters and histopathological lesions in skin and liver tissues of camel milk-treated mice. Additionally, a marked decrease (p<0.005; 0.001) in LPO levels and an increase in GSH, catalase and SOD biochemical parameters were noted. Moreover, dose-dependent elevation (p<0.001) of milk's anti-oxidative activity (DPPH, ABTS, ferrous-ion & superoxide-anion chelating) and presence of numerous anti-oxidative and anticancer compounds was observed. DISCUSSIONS: The investigation highlights translational relevance of camel milk's in-vitro outcomes as supported by in-vivo findings. Moreover, GC-MS analysis and anti-oxidative potential underscore the mechanism behind the observed chemo-prevention.

conclusionsThe study reveals camel milk's significant chemo-preventive efficacy primarily due to its robust antioxidant properties, making it a promising adjunct skin cancer therapy.

Indexed as

Antineoplastic AgentsAntioxidantsMilkSkin NeoplasmsAnimalsCamelusCell CycleCell MovementCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMiceMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsAntioxidantsA431 cellsantioxidantsanti-proliferativeCamel milkskin cancer therapytwo-stage skin carcinogenesis

Identifiers

PMID41121517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.