ReviewCurrent cardiology reviews2026
Contemporary Review of Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement with Concomitant Mitral Stenosis.
Review in Current cardiology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
introductionMultivalvular cardiac disease has been associated with increased mortality and morbidity as compared to isolated valve disease. The treatment of choice for combined degenerative aortic and mitral stenotic disease is considered to be double valve surgery, but it is associated with poorer outcomes when compared to isolated valve surgical correction, especially in high-risk populations. There is considerable interest in utilizing transcatheter therapies in multivalvular disease. The prevalence and outcomes of patients undergoing transcatheter aortic valve replacement (TAVR) for aortic stenosis (AS) with concomitant mitral stenosis (MS) have not been studied extensively. Currently, there are no specific recommendations or guidelines for managing these patients.
methodsA search of PubMed and Cochrane databases was performed for clinical studies of patients undergoing TAVR for severe AS with concomitant MS.
resultsOur research demonstrates that most patients undergoing TAVR for severe AS with concomitant mitral valve stenosis tend to be elderly with degenerative valve disease. Short-term outcomes, such as postoperative hospital stay, as well as long-term outcomes, such as 1-year mortality, are worse in TAVR with severe MS. TAVR in mild to moderate MS shows no significant differences in outcomes compared with TAVR for isolated severe AS. DISCUSSION: Most studies have shown that in subjects undergoing TAVR with concomitant MS, severe MS is associated with worse outcomes, while mild to moderate MS shows no significant difference compared with the absence of MS. Limitations of our study are mainly related to the small number of high-quality clinical trials examining TAVR in patients with combined AS and MS.
conclusionWith the aging population, TAVR has been a more attractive option for the treatment of severe symptomatic AS. The optimal treatment of patients with AS along with MS is not clear. Thus, further research is needed in this field.
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