Evidence map›Paper›PMID 41121499›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Comparative outcomes of direct anastomosis versus patch repair in neonatal aortic arch reconstruction: Freedom from restenosis and reintervention.

Aybala Tongut, Zeynep Bengi Eren, Mahmut Ozturk, Alyssia Venna, Mitchell Haverty, Arif Selcuk, Manan Desai, Andrew Waberski, Can Yerebakan, Yves d'Udekem

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Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Aybala TongutDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Zeynep Bengi ErenDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Mahmut OzturkDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Alyssia VennaDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Mitchell HavertyDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Arif SelcukDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Manan DesaiDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Andrew WaberskiDepartment of Anesthesiology, Pain, and Perioperative Medicine, Children's National Hospital, Washington, DC, USA.
Can YerebakanDivision of Cardiothoracic Surgery, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA.
Yves d'UdekemDivision of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study compares outcomes of patch repair versus direct anastomosis in neonatal aortic arch repair with the goal of identifying any long-term differences in restenosis, reoperation, and reintervention rates.

methodsNeonates who underwent aortic arch repair via median sternotomy between 2004 and 2021, using either patch repair or direct anastomosis techniques, were included in this study. Patch materials were glutaraldehyde-treated pericardium and femoral vein homograft. Statistical comparisons included descriptive and bivariable analyses to evaluate patient characteristics, reintervention, reoperation, and restenosis at a 20 mmHg threshold.

resultsSeventy-five neonates, who underwent neonatal arch repair using patch technique (n = 53) or direct anastomosis (n = 22) were included in the study. No significant differences in reintervention, reoperation, or restenosis were found between surgical approaches at 20 mmHg threshold (p > 0.13). Patient characteristics such as younger age (p = 0.06), shorter height (p = 0.1), and lower weight (p = 0.2), at the time of surgery were not significant predictors of restenosis. Cardiopulmonary bypass and circulatory arrest times were shorter with direct anastomosis. Ten-year mortality was 11% (n = 8).

conclusionsThere is no clear advantage of either patch or direct anastomosis for neonatal aortic arch repair regarding early- to mid-term outcomes. Patient-specific factors did not appear to be stronger predictors of restenosis risk than the surgical technique employed.

Indexed as

Coarctation of the aortadirect anastomosisend to end repairneonatal aortic arch repairreinterventionrestenosis

Identifiers

PMID41121499
PMCPMC12574784

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