ArticleCardio-oncology (London, England)2025
Radiation- and age-related vascular dysfunction as an early indicator of cardiovascular risk: a long-term study in the ApoE
Article in Cardio-oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association of radiation exposure and blood lipid derived indices with hypertension risk in radiation workers.Frontiers in public health · 2026Article
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3 authors.
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Abstract
backgroundDespite advances in radiotherapeutic techniques, radiation-induced cardiovascular diseases (CVD) remain a leading but often underrecognized cause of morbidity and mortality in cancer survivors. Radiation exposure can trigger a broad spectrum of cardiotoxic effects yet clinical awareness and strategies for managing these long-term complications remain limited. Among emerging indicators of vascular dysfunction, measures of vascular flexibility offer key biomarkers for assessing vascular compliance and cardiovascular risk.
methodsThe present study hence investigated age- and dose-dependent effects of local irradiation on vascular function of the murine Arteria saphena in C57BL/6 wild-type and atherosclerosis-prone apolipoprotein E-knockout (ApoE
resultsBaseline arterial diameters declined with age in both strains, with earlier onset in ApoE
conclusionBoth mouse strains exhibited marked age-related vascular changes, with ApoE
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