Evidence map›Paper›PMID 41121441›Full record

ReviewJournal of medical case reports2025

Long-term survival of nonoccupational pleural mesothelioma: a case report and review of the literature.

Loreta Tobia, Elio Tolli, Adalgisa Ilaria Sedile, Vincenza Cofini, Stefano Necozione, Leila Fabiani

Abstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Loreta TobiaDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Via Giuseppe Petrini 1, 67010, Coppito, AQ, Italy. loreta.tobia@univaq.it.
Elio TolliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Via Giuseppe Petrini 1, 67010, Coppito, AQ, Italy.
Adalgisa Ilaria SedileDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Via Giuseppe Petrini 1, 67010, Coppito, AQ, Italy.
Vincenza CofiniDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Via Giuseppe Petrini 1, 67010, Coppito, AQ, Italy.
Stefano NecozioneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Via Giuseppe Petrini 1, 67010, Coppito, AQ, Italy.
Leila FabianiDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Via Giuseppe Petrini 1, 67010, Coppito, AQ, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMalignant mesothelioma is an aggressive cancer that arises from the mesothelial cells lining the pleura, peritoneum, pericardium, or tunica vaginalis. While occupational exposure accounts for most cases, nonoccupational exposures (to ionizing radiation, carbon nanotubes, and different natural fibers) remain important and under-recognized. The rarity of nonoccupational pleural mesothelioma cases with prolonged survival substantiates a detailed analysis of the presented clinical case to increase awareness and review and contribute to the scientific literature. CASE PRESENTATION: We present a clinical case of a 64-year-old Caucasian male patient still alive after a diagnosis in 2017 of epithelial-type pleural mesothelioma and three episodes of pleuritis accompanied by dyspnea, fever, and chest pain. The patient lived near a contaminated area but no other exposure was reported. The diagnosis was established by thoracic computed tomography scan and thoracentesis. The patient subsequently underwent chemotherapy and pneumonectomy, followed by semiannual follow-up visits that showed no evidence of disease recurrence.

conclusionThis case highlights the importance of considering nonoccupational risk factors in patients with pleural mesothelioma and suggests that long-term survival can be achieved with early diagnosis and multimodal treatment. This literature review supports the need for further studies to improve the understanding and management of nonoccupational pleural mesothelioma.

Indexed as

Lung NeoplasmsMesotheliomaMesothelioma, MalignantPleural NeoplasmsHumansMaleMiddle AgedPneumonectomyThoracentesisTomography, X-Ray ComputedCase reportOccupational and non-occupational risk factors for mesotheliomaPleural mesotheliomaSurvivalSynchronous tumors with mesothelioma

Identifiers

PMID41121441
PMCPMC12542408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.