Evidence map›Paper›PMID 41121415›Full record

ArticleEuropean journal of medical research2025

Unveiling the role of lumbar intervertebral space morphology: a novel classification and its impact on cage migration in lumbar fusion surgery.

Yang Hou, Lei Liu, Tianyi Zhao, Yongfei Guo, Jiangang Shi

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yang Hou *Department of Orthopaedic Surgery, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Rd, Shanghai, 200003, China.
Lei Liu *Department of Orthopaedic Surgery, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Rd, Shanghai, 200003, China.
Tianyi ZhaoDepartment of Orthopaedic Surgery, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Rd, Shanghai, 200003, China.
Yongfei GuoDepartment of Orthopaedic Surgery, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Rd, Shanghai, 200003, China. Junjiespine@sina.com.
Jiangang ShiDepartment of Orthopaedic Surgery, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Rd, Shanghai, 200003, China. Alexzandersuper@163.com.

Funding

Shanghai Municipal Health Commission 202340128
6 · The paper itself

Abstract

purposeThis study aimed to establish a novel classification system for lumbar intervertebral spaces based on anatomical morphology, to investigate the relationship between intervertebral space types and cage migration risk after transforaminal lumbar interbody fusion (TLIF), and to optimize fusion strategies tailored to different anatomical types.

methodsA retrospective cohort study was conducted on 103 patients who underwent TLIF between February 2022 and June 2023. Lumbar intervertebral spaces were classified into 3 fundamental types: lordotic, neutral and kyphotic and 2 modified types: normal and degenerative. Clinical outcomes (Visual Analogue Scale [VAS], Oswestry Disability Index [ODI]), and radiographic parameters (Intervertebral Space Angle [ISA], Intervertebral Space Height [ISH], Intervertebral Foramen Height [IFH]) were evaluated. Statistical analyses included t tests, ANOVA, chi-square tests, and logistic regression.

resultsVAS and ODI scores significantly improved postoperatively (P < 0.05). ISA, ISH, and IFH showed significant postoperative increases across all fundamental types. Cage migration occurred in 8 segments, predominantly in degenerative-type intervertebral spaces. Logistic regression revealed that the degenerative type was associated with a 17-fold increased risk of cage migration (OR = 17.02). No significant association was found between fundamental type and migration. Fusion rates exceeded 98% across all groups.

conclusionThe novel classification of lumbar intervertebral spaces effectively predicts cage migration risk. The degenerative modified type is a strong risk factor for migration. Tailoring surgical strategies to intervertebral space morphology may improve stability and outcomes in lumbar interbody fusion procedures.

Indexed as

Lumbar VertebraeSpinal FusionAdultAgedFemaleHumansLumbosacral RegionMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesCage migrationDegenerative endplateIntervertebral space classificationLumbar interbody fusionTransforaminal lumbar interbody fusion (TLIF)

Identifiers

PMID41121415
PMCPMC12542467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.