Evidence map›Paper›PMID 41121337›Full record

ArticleWorld journal of surgical oncology2025

Indocyanine green-assisted liver resection for colorectal liver metastases and factors associated with resection margin: a single-center retrospective study.

Lei Yang, Yufan Yang, Xuechen Liu, Jingyi Xu, Wenqiang Wang, Liusheng Wu, Jun Yan

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PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lei Yang *Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China. yang-l23@mails.tsinghua.edu.cn.
Yufan Yang *Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Xuechen Liu *The First Affiliated Hospital of Tsinghua University, School of Clinical Medicine, Tsinghua University, Beijing, 100016, China.
Jingyi XuBeijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Wenqiang WangBeijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Liusheng WuBeijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China. wuliusheng852@126.com.
Jun YanBeijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China. yanjun1619@tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to compare the short-term outcomes of Indocyanine Green (ICG) assisted minimally invasive surgery (MIS) with Intraoperative Ultrasound (IOUS) against conventional MIS with IOUS alone and open surgery with tactility and IOUS for colorectal liver metastases (CRLM). And identify risk factor of R1 resection (tumor-negative margin < 1 mm) by statistical analysis. MATERIALS AND

methodsA retrospective cohort analysis was conducted on 86 patients with 158 CRLM tumors undergoing hepatectomy. Patients were categorized into three groups: Group A (ICG + IOUS MIS, n = 14, tumor = 23), Group B (IOUS only MIS, n = 16, tumor = 20), and Group C (tactile + IOUS Open surgery, n = 56, tumor = 115). Statistical analysis involved univariate analysis and multivariable logistic regression were performed.

resultsGroup A demonstrated superior R0 resection (tumor-negative margin ≥ 1 mm) rates, shorter median hospital stays compared to Groups C. Intraoperatively, Group A exhibited reduced blood loss and shorter operative times (213.5 vs. 351.5 min, p = 0.02) compared to Group C. Multivariable analysis identified surgical approach, lower Ki-67 expression, higher body weight and more metastatic lesions as independent predictors of R1 resection.

conclusionICG assisted MIS significantly reduces R1 resection rates, postoperative hospitalization time and costs compared to conventional MIS or open surgery.

Indexed as

Colorectal NeoplasmsHepatectomyIndocyanine GreenLiver NeoplasmsMinimally Invasive Surgical ProceduresAdultAgedColoring AgentsFemaleFollow-Up StudiesHumansLength of StayMaleMargins of ExcisionMiddle AgedOperative TimeColoring AgentsIndocyanine GreenColorectal liver metastasesIndocyanine greenR0 resection

Identifiers

PMID41121337
PMCPMC12538843

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.