Evidence map›Paper›PMID 41121326›Full record

ArticleJournal of orthopaedic surgery and research2025

Higher graft failure rates following primary ACL reconstruction and conservative MCL treatment compared to simultaneous primary ACL and MCL reconstruction: a retrospective cohort study.

Mohammad Razi, Mohammad Soleimani, Haleh Dadgostar, Saeed Razi

Abstract readComparative Study
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Mohammad RaziDepartment of Orthopaedic Surgery, Rasoul Akram Hospital, University of Medical Sciences, Tehran, Iran. mrazi@razimd.info.
Mohammad SoleimaniDepartment of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Haleh DadgostarDepartment of Sports and Exercise Medicine, Rasoul Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Saeed RaziJoint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCombined anterior cruciate ligament (ACL) and medial collateral ligament (MCL) injury is the most common combination of ligamentous knee injury. Many authors support the conservative treatment of MCL tears. This study aimed to compare the outcomes of simultaneous ACL reconstruction (ACL-R) and MCL reconstruction with ACL-R and conservative MCL treatment in cases of combined ACL and grade III MCL injuries.

methodsIn this retrospective cohort study, we evaluated consecutive patients with combined ACL and MCL injuries who underwent surgical treatment over five years in two private hospitals in Tehran, Iran. We compared postoperative knee range of motion (ROM), pain intensity (visual analog scale [VAS]), functional outcomes (Tegner-Lysholm and International Knee Documentation Committee Subjective Knee Form [IKDC] scores), time to and proportion of return to sports, time to return to work, activity level (Marx activity rating scale), and graft failure rate between ACL-R and conservative MCL treatment (ACL-R + conservative MCL group) and ACL-R and MCL reconstruction (ACL-R + MCL-R group). All patients were followed for at least twelve months.

resultsOverall, 110 patients, comprising 92 men (83.6%) and 18 women (16.4%), were included, consisting of 67 (60.9%) in the ACL-R + conservative MCL group and 43 (39.1%) in the ACL-R + MCL-R group. The mean age of the patients was 27.5 ± 9.0 years. Age, sex, side, and follow-up period were comparable between the groups (P > 0.05 for all). Graft failure occurred in 6 patients (9.0%) in the ACL-R + conservative MCL group, but in none of the patients in the ACL-R + MCL-R group (P = 0.046). Range of extension and flexion of the knee, VAS, Tegner-Lysholm score, IKDC score, time to return to sports, time to return to work, proportion of return to sports, and activity level did not differ significantly between the groups (P > 0.05 for all).

conclusionACL-R and MCL reconstruction resulted in similar knee ROM, pain intensity, functional outcomes, time to return to work and sports, and activity level to ACL-R and conservative MCL treatment in patients with combined ACL and MCL injury. However, ACL-R and MCL reconstruction significantly reduced graft failure rates, suggesting the potential benefit of surgical MCL management in conjunction with ACL reconstruction.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionConservative TreatmentGraft RejectionMedial Collateral Ligament, KneeAdolescentAdultCohort StudiesFemaleHumansMaleRange of Motion, ArticularRetrospective StudiesYoung AdultACL reconstructionAnterior cruciate ligamentArthroscopyGraft failureMedial collateral ligament

Identifiers

PMID41121326
PMCPMC12538881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.