Evidence map›Paper›PMID 41121285›Full record

ArticleHarm reduction journal2025

HIV vaulnerability among people who inject drugs (PWID): findings from the Bangladesh integrated biological and behavioural surveillance (IBBS) study 2020.

Jessica Srivastava, Md Nazmul Karim, Fariha Haseen, Md Hasan, Md Golam Rabbani, Farhana Sultana, Md Shakawat Alam, Sibgha Fatima, Saif Ullah Munshi, National AIDS/STD Programme (NASP)

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Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

10 authors.

Jessica Srivastava *School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Md Nazmul Karim *School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. nazmul.karim@monash.edu.
Fariha HaseenDepartment of Virology, Bangladesh Medical University, Dhaka, Bangladesh.
Md HasanDepartment of Public Health and Informatics, Bangladesh Medical University, Dhaka, Bangladesh.
Md Golam RabbaniSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Farhana SultanaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Md Shakawat AlamDepartment of Virology, Bangladesh Medical University, Dhaka, Bangladesh.
Sibgha FatimaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Saif Ullah MunshiDepartment of Virology, Bangladesh Medical University, Dhaka, Bangladesh. saifmunshi@bsmmu.edu.bd.
National AIDS/STD Programme (NASP)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeople who inject drugs (PWID) contribute significantly to the global HIV burden. Various individual and contextual factors exacerbate the risk of HIV among PWID, this problem is particularly acute in low- and middle-income countries, where resource constraints impede effective prevention and treatment efforts. Although Bangladesh is classified as a low HIV prevalence country, and despite national efforts, including surveillance through the Integrated Biobehavioural Survey (IBBS), gaps in evidence and actionable insights persist. This study aims to analyse the latest IBBS 2020 data to identify risk factors associated with HIV vulnerability among PWID in Bangladesh, informing culturally relevant and targeted harm reduction strategies to mitigate these risks.

methodThis study analysed data from IBBS, which used a two-stage cluster sampling and Time Location Sampling methods to recruit participants. Data were collected across four domains: (1) Sociodemographic characteristics, (2) Drug and Injection-Related Behaviours, (3) Sexual Behaviours, and (4) Co-infections, with blood samples collected for HIV, hepatitis-C, and syphilis serological testing. Sample weights were applied to adjust for the complex survey design. Descriptive statistics summarized participant characteristics and risk behaviours. Two binary logistic regression models were used to identify HIV risk factors: The Fully Adjusted Model, which included all plausible confounders and used the Wald backward elimination method to determine significant predictors, and the Partially Adjusted Model, which controlled for age, gender, and education to explore intermediate factors through adjusting confounding or mediation.

resultOverall, the prevalence of HIV among PWID was 4.1%. Social exclusion (AOR: 1.71, 95% CI 1.1, 2.7). Hepatitis C infection (AOR: 2.57, 95% CI 1.6, 4.0), drug use of more than 10 years (AOR: 3.74, 95% CI 1.3, 10.8), injecting once or more daily (AOR: 5.23, 95% CI 2.6, 10.7), having multiple injecting partners (AOR: 3.11, 95% CI 1.8, 5.3) sharing injecting accessories (AOR: 2.55, 95% CI 1.5, 4.4) and engaging with a commercial sex partner (AOR: 1.80, 95% CI 1.1, 2.9) emerged as significant predictors of HIV risk among PWID patients.

conclusionThis study reveals the heightened HIV risk among PWID in Bangladesh, driven by intertwined social, behavioural, biological, and structural factors. It underscores the urgent need for tailored, holistic interventions combining harm reduction, structural reforms, and biomedical strategies to address vulnerabilities, reduce high-risk behaviours, and improve healthcare access for this marginalized group.

Indexed as

HIV InfectionsSubstance Abuse, IntravenousAdolescentAdultBangladeshCoinfectionFemaleHarm ReductionHepatitis CHumansMaleMiddle AgedPrevalenceRisk FactorsSexual BehaviorYoung AdultBangladeshHigh risk behaviourHIVIBBSPWID

Identifiers

PMID41121285
PMCPMC12538887

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LicenceCC BY-NC-ND
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